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Loss of Hem1 disrupts macrophage function and impacts migration, phagocytosis, and integrin-mediated adhesion.
Stahnke S, Döring H, Kusch C, de Gorter DJJ, Dütting S, Guledani A, Pleines I, Schnoor M, Sixt M, Geffers R, Rohde M, Müsken M, Kage F, Steffen A, Faix J, Nieswandt B, Rottner K, Stradal TEB. Stahnke S, et al. Among authors: pleines i. Curr Biol. 2021 May 24;31(10):2051-2064.e8. doi: 10.1016/j.cub.2021.02.043. Epub 2021 Mar 11. Curr Biol. 2021. PMID: 33711252 Free article.
Cell adhesion mechanisms in platelets.
Varga-Szabo D, Pleines I, Nieswandt B. Varga-Szabo D, et al. Among authors: pleines i. Arterioscler Thromb Vasc Biol. 2008 Mar;28(3):403-12. doi: 10.1161/ATVBAHA.107.150474. Epub 2008 Jan 3. Arterioscler Thromb Vasc Biol. 2008. PMID: 18174460 Review.
RhoA/ROCK guides NMII on the way to MK polyploidy.
Pleines I, Nieswandt B. Pleines I, et al. Blood. 2016 Dec 29;128(26):3025-3026. doi: 10.1182/blood-2016-11-746685. Blood. 2016. PMID: 28034868 Free article. No abstract available.
Impaired microtubule dynamics contribute to microthrombocytopenia in RhoB-deficient mice.
Englert M, Aurbach K, Becker IC, Gerber A, Heib T, Wackerbarth LM, Kusch C, Mott K, Araujo GHM, Baig AA, Dütting S, Knaus UG, Stigloher C, Schulze H, Nieswandt B, Pleines I, Nagy Z. Englert M, et al. Among authors: pleines i. Blood Adv. 2022 Sep 13;6(17):5184-5197. doi: 10.1182/bloodadvances.2021006545. Blood Adv. 2022. PMID: 35819450 Free PMC article.
RhoA/Cdc42 signaling drives cytoplasmic maturation but not endomitosis in megakaryocytes.
Heib T, Hermanns HM, Manukjan G, Englert M, Kusch C, Becker IC, Gerber A, Wackerbarth LM, Burkard P, Dandekar T, Balkenhol J, Jahn D, Beck S, Meub M, Dütting S, Stigloher C, Sauer M, Cherpokova D, Schulze H, Brakebusch C, Nieswandt B, Nagy Z, Pleines I. Heib T, et al. Among authors: pleines i. Cell Rep. 2021 May 11;35(6):109102. doi: 10.1016/j.celrep.2021.109102. Cell Rep. 2021. PMID: 33979620 Free article.
38 results