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Dual IRE1 RNase functions dictate glioblastoma development.
Lhomond S, Avril T, Dejeans N, Voutetakis K, Doultsinos D, McMahon M, Pineau R, Obacz J, Papadodima O, Jouan F, Bourien H, Logotheti M, Jégou G, Pallares-Lupon N, Schmit K, Le Reste PJ, Etcheverry A, Mosser J, Barroso K, Vauléon E, Maurel M, Samali A, Patterson JB, Pluquet O, Hetz C, Quillien V, Chatziioannou A, Chevet E. Lhomond S, et al. Among authors: pineau r. EMBO Mol Med. 2018 Mar;10(3):e7929. doi: 10.15252/emmm.201707929. EMBO Mol Med. 2018. PMID: 29311133 Free PMC article.
Alterations of EDEM1 functions enhance ATF6 pro-survival signaling.
Papaioannou A, Higa A, Jégou G, Jouan F, Pineau R, Saas L, Avril T, Pluquet O, Chevet E. Papaioannou A, et al. Among authors: pineau r. FEBS J. 2018 Nov;285(22):4146-4164. doi: 10.1111/febs.14669. Epub 2018 Oct 20. FEBS J. 2018. PMID: 30281916 Free article.
CD90 Expression Controls Migration and Predicts Dasatinib Response in Glioblastoma.
Avril T, Etcheverry A, Pineau R, Obacz J, Jegou G, Jouan F, Le Reste PJ, Hatami M, Colen RR, Carlson BL, Decker PA, Sarkaria JN, Vauléon E, Chiforeanu DC, Clavreul A, Mosser J, Chevet E, Quillien V. Avril T, et al. Among authors: pineau r. Clin Cancer Res. 2017 Dec 1;23(23):7360-7374. doi: 10.1158/1078-0432.CCR-17-1549. Epub 2017 Sep 22. Clin Cancer Res. 2017. PMID: 28939749 Free article.
Glioblastoma invasion and cooption depend on IRE1α endoribonuclease activity.
Jabouille A, Delugin M, Pineau R, Dubrac A, Soulet F, Lhomond S, Pallares-Lupon N, Prats H, Bikfalvi A, Chevet E, Touriol C, Moenner M. Jabouille A, et al. Among authors: pineau r. Oncotarget. 2015 Sep 22;6(28):24922-34. doi: 10.18632/oncotarget.4679. Oncotarget. 2015. PMID: 26325176 Free PMC article.
Local intracerebral inhibition of IRE1 by MKC8866 sensitizes glioblastoma to irradiation/chemotherapy in vivo.
Le Reste PJ, Pineau R, Voutetakis K, Samal J, Jégou G, Lhomond S, Gorman AM, Samali A, Patterson JB, Zeng Q, Pandit A, Aubry M, Soriano N, Etcheverry A, Chatziioannou A, Mosser J, Avril T, Chevet E. Le Reste PJ, et al. Among authors: pineau r. Cancer Lett. 2020 Dec 1;494:73-83. doi: 10.1016/j.canlet.2020.08.028. Epub 2020 Sep 1. Cancer Lett. 2020. PMID: 32882336
Inositol-requiring enzyme 1alpha is a key regulator of angiogenesis and invasion in malignant glioma.
Auf G, Jabouille A, Guérit S, Pineau R, Delugin M, Bouchecareilh M, Magnin N, Favereaux A, Maitre M, Gaiser T, von Deimling A, Czabanka M, Vajkoczy P, Chevet E, Bikfalvi A, Moenner M. Auf G, et al. Among authors: pineau r. Proc Natl Acad Sci U S A. 2010 Aug 31;107(35):15553-8. doi: 10.1073/pnas.0914072107. Epub 2010 Aug 11. Proc Natl Acad Sci U S A. 2010. PMID: 20702765 Free PMC article.
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