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Endoplasmic Reticulum Transport of Glutathione by Sec61 Is Regulated by Ero1 and Bip.
Ponsero AJ, Igbaria A, Darch MA, Miled S, Outten CE, Winther JR, Palais G, D'Autréaux B, Delaunay-Moisan A, Toledano MB. Ponsero AJ, et al. Among authors: igbaria a. Mol Cell. 2017 Sep 21;67(6):962-973.e5. doi: 10.1016/j.molcel.2017.08.012. Epub 2017 Sep 14. Mol Cell. 2017. PMID: 28918898 Free PMC article.
Allosteric inhibition of the IRE1α RNase preserves cell viability and function during endoplasmic reticulum stress.
Ghosh R, Wang L, Wang ES, Perera BG, Igbaria A, Morita S, Prado K, Thamsen M, Caswell D, Macias H, Weiberth KF, Gliedt MJ, Alavi MV, Hari SB, Mitra AK, Bhhatarai B, Schürer SC, Snapp EL, Gould DB, German MS, Backes BJ, Maly DJ, Oakes SA, Papa FR. Ghosh R, et al. Among authors: igbaria a. Cell. 2014 Jul 31;158(3):534-48. doi: 10.1016/j.cell.2014.07.002. Epub 2014 Jul 10. Cell. 2014. PMID: 25018104 Free PMC article.
IRE1α induces thioredoxin-interacting protein to activate the NLRP3 inflammasome and promote programmed cell death under irremediable ER stress.
Lerner AG, Upton JP, Praveen PV, Ghosh R, Nakagawa Y, Igbaria A, Shen S, Nguyen V, Backes BJ, Heiman M, Heintz N, Greengard P, Hui S, Tang Q, Trusina A, Oakes SA, Papa FR. Lerner AG, et al. Among authors: igbaria a. Cell Metab. 2012 Aug 8;16(2):250-64. doi: 10.1016/j.cmet.2012.07.007. Cell Metab. 2012. PMID: 22883233 Free PMC article.
16 results