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CACNA1I gain-of-function mutations differentially affect channel gating and cause neurodevelopmental disorders.
Brain. 2021 Aug 17;144(7):2092-2106. doi: 10.1093/brain/awab101.
Brain. 2021.
PMID: 33704440
Free PMC article.
Correcting the R165K substitution in the first voltage-sensor of CaV1.1 right-shifts the voltage-dependence of skeletal muscle calcium channel activation.
El Ghaleb Y, Campiglio M, Flucher BE.
El Ghaleb Y, et al.
Channels (Austin). 2019 Dec;13(1):62-71. doi: 10.1080/19336950.2019.1568825.
Channels (Austin). 2019.
PMID: 30638110
Free PMC article.
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Structural determinants of voltage-gating properties in calcium channels.
Fernández-Quintero ML, El Ghaleb Y, Tuluc P, Campiglio M, Liedl KR, Flucher BE.
Fernández-Quintero ML, et al. Among authors: el ghaleb y.
Elife. 2021 Mar 30;10:e64087. doi: 10.7554/eLife.64087.
Elife. 2021.
PMID: 33783354
Free PMC article.
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Ion-pair interactions between voltage-sensing domain IV and pore domain I regulate CaV1.1 gating.
El Ghaleb Y, Fernández-Quintero ML, Monteleone S, Tuluc P, Campiglio M, Liedl KR, Flucher BE.
El Ghaleb Y, et al.
Biophys J. 2021 Oct 19;120(20):4429-4441. doi: 10.1016/j.bpj.2021.09.004. Epub 2021 Sep 8.
Biophys J. 2021.
PMID: 34506774
Free PMC article.
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Calcium current modulation by the γ1 subunit depends on alternative splicing of CaV1.1.
El Ghaleb Y, Ortner NJ, Posch W, Fernández-Quintero ML, Tuinte WE, Monteleone S, Draheim HJ, Liedl KR, Wilflingseder D, Striessnig J, Tuluc P, Flucher BE, Campiglio M.
El Ghaleb Y, et al.
J Gen Physiol. 2022 Sep 5;154(9):e202113028. doi: 10.1085/jgp.202113028. Epub 2022 Mar 29.
J Gen Physiol. 2022.
PMID: 35349630
Free PMC article.
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CaV3.3 Channelopathies.
El Ghaleb Y, Flucher BE.
El Ghaleb Y, et al.
Handb Exp Pharmacol. 2023;279:263-288. doi: 10.1007/164_2022_631.
Handb Exp Pharmacol. 2023.
PMID: 36592228
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