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Channelling inflammation: gasdermins in physiology and disease.
Liu X, Xia S, Zhang Z, Wu H, Lieberman J. Liu X, et al. Among authors: xia s. Nat Rev Drug Discov. 2021 May;20(5):384-405. doi: 10.1038/s41573-021-00154-z. Epub 2021 Mar 10. Nat Rev Drug Discov. 2021. PMID: 33692549 Free PMC article. Review.
Cryo-EM structure of the gasdermin A3 membrane pore.
Ruan J, Xia S, Liu X, Lieberman J, Wu H. Ruan J, et al. Among authors: xia s. Nature. 2018 May;557(7703):62-67. doi: 10.1038/s41586-018-0058-6. Epub 2018 Apr 25. Nature. 2018. PMID: 29695864 Free PMC article.
Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death.
Orning P, Weng D, Starheim K, Ratner D, Best Z, Lee B, Brooks A, Xia S, Wu H, Kelliher MA, Berger SB, Gough PJ, Bertin J, Proulx MM, Goguen JD, Kayagaki N, Fitzgerald KA, Lien E. Orning P, et al. Among authors: xia s. Science. 2018 Nov 30;362(6418):1064-1069. doi: 10.1126/science.aau2818. Epub 2018 Oct 25. Science. 2018. PMID: 30361383 Free PMC article.
Structures and gating mechanism of human TRPM2.
Wang L, Fu TM, Zhou Y, Xia S, Greka A, Wu H. Wang L, et al. Among authors: xia s. Science. 2018 Dec 21;362(6421):eaav4809. doi: 10.1126/science.aav4809. Epub 2018 Nov 22. Science. 2018. PMID: 30467180 Free PMC article.
Mechanism and Regulation of Gasdermin-Mediated Cell Death.
Xia S, Hollingsworth LR 4th, Wu H. Xia S, et al. Cold Spring Harb Perspect Biol. 2020 Mar 2;12(3):a036400. doi: 10.1101/cshperspect.a036400. Cold Spring Harb Perspect Biol. 2020. PMID: 31451512 Free PMC article. Review.
Monitoring gasdermin pore formation in vitro.
Xia S, Ruan J, Wu H. Xia S, et al. Methods Enzymol. 2019;625:95-107. doi: 10.1016/bs.mie.2019.04.024. Epub 2019 May 23. Methods Enzymol. 2019. PMID: 31455540 Free PMC article.
4,135 results