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Chromatin extrusion explains key features of loop and domain formation in wild-type and engineered genomes.
Sanborn AL, Rao SS, Huang SC, Durand NC, Huntley MH, Jewett AI, Bochkov ID, Chinnappan D, Cutkosky A, Li J, Geeting KP, Gnirke A, Melnikov A, McKenna D, Stamenova EK, Lander ES, Aiden EL. Sanborn AL, et al. Among authors: aiden el. Proc Natl Acad Sci U S A. 2015 Nov 24;112(47):E6456-65. doi: 10.1073/pnas.1518552112. Epub 2015 Oct 23. Proc Natl Acad Sci U S A. 2015. PMID: 26499245 Free PMC article.
Deletion of DXZ4 on the human inactive X chromosome alters higher-order genome architecture.
Darrow EM, Huntley MH, Dudchenko O, Stamenova EK, Durand NC, Sun Z, Huang SC, Sanborn AL, Machol I, Shamim M, Seberg AP, Lander ES, Chadwick BP, Aiden EL. Darrow EM, et al. Among authors: aiden el. Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):E4504-12. doi: 10.1073/pnas.1609643113. Epub 2016 Jul 18. Proc Natl Acad Sci U S A. 2016. PMID: 27432957 Free PMC article.
Cohesin Loss Eliminates All Loop Domains.
Rao SSP, Huang SC, Glenn St Hilaire B, Engreitz JM, Perez EM, Kieffer-Kwon KR, Sanborn AL, Johnstone SE, Bascom GD, Bochkov ID, Huang X, Shamim MS, Shin J, Turner D, Ye Z, Omer AD, Robinson JT, Schlick T, Bernstein BE, Casellas R, Lander ES, Aiden EL. Rao SSP, et al. Among authors: aiden el. Cell. 2017 Oct 5;171(2):305-320.e24. doi: 10.1016/j.cell.2017.09.026. Cell. 2017. PMID: 28985562 Free PMC article.
Hybrid de novo genome assembly and centromere characterization of the gray mouse lemur (Microcebus murinus).
Larsen PA, Harris RA, Liu Y, Murali SC, Campbell CR, Brown AD, Sullivan BA, Shelton J, Brown SJ, Raveendran M, Dudchenko O, Machol I, Durand NC, Shamim MS, Aiden EL, Muzny DM, Gibbs RA, Yoder AD, Rogers J, Worley KC. Larsen PA, et al. Among authors: aiden el. BMC Biol. 2017 Nov 16;15(1):110. doi: 10.1186/s12915-017-0439-6. BMC Biol. 2017. PMID: 29145861 Free PMC article.
Improved reference genome of Aedes aegypti informs arbovirus vector control.
Matthews BJ, Dudchenko O, Kingan SB, Koren S, Antoshechkin I, Crawford JE, Glassford WJ, Herre M, Redmond SN, Rose NH, Weedall GD, Wu Y, Batra SS, Brito-Sierra CA, Buckingham SD, Campbell CL, Chan S, Cox E, Evans BR, Fansiri T, Filipović I, Fontaine A, Gloria-Soria A, Hall R, Joardar VS, Jones AK, Kay RGG, Kodali VK, Lee J, Lycett GJ, Mitchell SN, Muehling J, Murphy MR, Omer AD, Partridge FA, Peluso P, Aiden AP, Ramasamy V, Rašić G, Roy S, Saavedra-Rodriguez K, Sharan S, Sharma A, Smith ML, Turner J, Weakley AM, Zhao Z, Akbari OS, Black WC 4th, Cao H, Darby AC, Hill CA, Johnston JS, Murphy TD, Raikhel AS, Sattelle DB, Sharakhov IV, White BJ, Zhao L, Aiden EL, Mann RS, Lambrechts L, Powell JR, Sharakhova MV, Tu Z, Robertson HM, McBride CS, Hastie AR, Korlach J, Neafsey DE, Phillippy AM, Vosshall LB. Matthews BJ, et al. Among authors: aiden el, aiden ap. Nature. 2018 Nov;563(7732):501-507. doi: 10.1038/s41586-018-0692-z. Epub 2018 Nov 14. Nature. 2018. PMID: 30429615 Free PMC article.
The genome sequence of segmental allotetraploid peanut Arachis hypogaea.
Bertioli DJ, Jenkins J, Clevenger J, Dudchenko O, Gao D, Seijo G, Leal-Bertioli SCM, Ren L, Farmer AD, Pandey MK, Samoluk SS, Abernathy B, Agarwal G, Ballén-Taborda C, Cameron C, Campbell J, Chavarro C, Chitikineni A, Chu Y, Dash S, El Baidouri M, Guo B, Huang W, Kim KD, Korani W, Lanciano S, Lui CG, Mirouze M, Moretzsohn MC, Pham M, Shin JH, Shirasawa K, Sinharoy S, Sreedasyam A, Weeks NT, Zhang X, Zheng Z, Sun Z, Froenicke L, Aiden EL, Michelmore R, Varshney RK, Holbrook CC, Cannon EKS, Scheffler BE, Grimwood J, Ozias-Akins P, Cannon SB, Jackson SA, Schmutz J. Bertioli DJ, et al. Among authors: el baidouri m, aiden el. Nat Genet. 2019 May;51(5):877-884. doi: 10.1038/s41588-019-0405-z. Epub 2019 May 1. Nat Genet. 2019. PMID: 31043755
Topologically Associated Domains Delineate Susceptibility to Somatic Hypermutation.
Senigl F, Maman Y, Dinesh RK, Alinikula J, Seth RB, Pecnova L, Omer AD, Rao SSP, Weisz D, Buerstedde JM, Aiden EL, Casellas R, Hejnar J, Schatz DG. Senigl F, et al. Among authors: aiden el. Cell Rep. 2019 Dec 17;29(12):3902-3915.e8. doi: 10.1016/j.celrep.2019.11.039. Cell Rep. 2019. PMID: 31851922 Free PMC article.
75 results