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Regulated IRE1-dependent mRNA decay sets the threshold for dendritic cell survival.
Tavernier SJ, Osorio F, Vandersarren L, Vetters J, Vanlangenakker N, Van Isterdael G, Vergote K, De Rycke R, Parthoens E, van de Laar L, Iwawaki T, Del Valle JR, Hu CC, Lambrecht BN, Janssens S. Tavernier SJ, et al. Among authors: janssens s. Nat Cell Biol. 2017 Jun;19(6):698-710. doi: 10.1038/ncb3518. Epub 2017 May 1. Nat Cell Biol. 2017. PMID: 28459443 Free PMC article.
IRE1β negatively regulates IRE1α signaling in response to endoplasmic reticulum stress.
Grey MJ, Cloots E, Simpson MS, LeDuc N, Serebrenik YV, De Luca H, De Sutter D, Luong P, Thiagarajah JR, Paton AW, Paton JC, Seeliger MA, Eyckerman S, Janssens S, Lencer WI. Grey MJ, et al. Among authors: janssens s. J Cell Biol. 2020 Feb 3;219(2):e201904048. doi: 10.1083/jcb.201904048. J Cell Biol. 2020. PMID: 31985747 Free PMC article.
Clarifying the translational potential of B-I09.
Del Valle JR, Betts BC, Yu XZ, Janssens S, Lambrecht BN, Simon MC, Hu CA. Del Valle JR, et al. Among authors: janssens s. Nat Chem Biol. 2020 Nov;16(11):1152. doi: 10.1038/s41589-020-00654-w. Nat Chem Biol. 2020. PMID: 33067597 Free PMC article. No abstract available.
The paradox of the unfolded protein response in cancer.
Vandewynckel YP, Laukens D, Geerts A, Bogaerts E, Paridaens A, Verhelst X, Janssens S, Heindryckx F, Van Vlierberghe H. Vandewynckel YP, et al. Among authors: janssens s. Anticancer Res. 2013 Nov;33(11):4683-94. Anticancer Res. 2013. PMID: 24222102 Review.
Modulation of the unfolded protein response impedes tumor cell adaptation to proteotoxic stress: a PERK for hepatocellular carcinoma therapy.
Vandewynckel YP, Laukens D, Bogaerts E, Paridaens A, Van den Bussche A, Verhelst X, Van Steenkiste C, Descamps B, Vanhove C, Libbrecht L, De Rycke R, Lambrecht BN, Geerts A, Janssens S, Van Vlierberghe H. Vandewynckel YP, et al. Among authors: janssens s. Hepatol Int. 2014 Oct 1;9(1):93-104. doi: 10.1007/s12072-014-9582-0. eCollection 2015 Jan. Hepatol Int. 2014. PMID: 25598862 Free PMC article.
726 results