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Cholesterol alters mitophagy by impairing optineurin recruitment and lysosomal clearance in Alzheimer's disease.
Mol Neurodegener. 2021 Mar 8;16(1):15. doi: 10.1186/s13024-021-00435-6.
Mol Neurodegener. 2021.
PMID: 33685483
Free PMC article.
Upregulation of brain cholesterol levels inhibits mitophagy in Alzheimer disease.
Roca-Agujetas V, de Dios C, Abadin X, Colell A.
Roca-Agujetas V, et al. Among authors: abadin x.
Autophagy. 2021 Jun;17(6):1555-1557. doi: 10.1080/15548627.2021.1920814. Epub 2021 May 4.
Autophagy. 2021.
PMID: 33945386
Free PMC article.
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Inflammasome activation under high cholesterol load triggers a protective microglial phenotype while promoting neuronal pyroptosis.
de Dios C, Abadin X, Roca-Agujetas V, Jimenez-Martinez M, Morales A, Trullas R, Mari M, Colell A.
de Dios C, et al. Among authors: abadin x.
Transl Neurodegener. 2023 Mar 9;12(1):10. doi: 10.1186/s40035-023-00343-3.
Transl Neurodegener. 2023.
PMID: 36895045
Free PMC article.
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