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Reactive astrocytes in ALS display diminished intron retention.
Ziff OJ, Taha DM, Crerar H, Clarke BE, Chakrabarti AM, Kelly G, Neeves J, Tyzack GE, Luscombe NM, Patani R. Ziff OJ, et al. Among authors: patani r. Nucleic Acids Res. 2021 Apr 6;49(6):3168-3184. doi: 10.1093/nar/gkab115. Nucleic Acids Res. 2021. PMID: 33684213 Free PMC article.
Progressive Motor Neuron Pathology and the Role of Astrocytes in a Human Stem Cell Model of VCP-Related ALS.
Hall CE, Yao Z, Choi M, Tyzack GE, Serio A, Luisier R, Harley J, Preza E, Arber C, Crisp SJ, Watson PMD, Kullmann DM, Abramov AY, Wray S, Burley R, Loh SHY, Martins LM, Stevens MM, Luscombe NM, Sibley CR, Lakatos A, Ule J, Gandhi S, Patani R. Hall CE, et al. Among authors: patani r. Cell Rep. 2017 May 30;19(9):1739-1749. doi: 10.1016/j.celrep.2017.05.024. Cell Rep. 2017. PMID: 28564594 Free PMC article.
Kir4.1-Dependent Astrocyte-Fast Motor Neuron Interactions Are Required for Peak Strength.
Kelley KW, Ben Haim L, Schirmer L, Tyzack GE, Tolman M, Miller JG, Tsai HH, Chang SM, Molofsky AV, Yang Y, Patani R, Lakatos A, Ullian EM, Rowitch DH. Kelley KW, et al. Among authors: patani r. Neuron. 2018 Apr 18;98(2):306-319.e7. doi: 10.1016/j.neuron.2018.03.010. Epub 2018 Apr 5. Neuron. 2018. PMID: 29606582 Free PMC article.
Three-Dimensional Human iPSC-Derived Artificial Skeletal Muscles Model Muscular Dystrophies and Enable Multilineage Tissue Engineering.
Maffioletti SM, Sarcar S, Henderson ABH, Mannhardt I, Pinton L, Moyle LA, Steele-Stallard H, Cappellari O, Wells KE, Ferrari G, Mitchell JS, Tyzack GE, Kotiadis VN, Khedr M, Ragazzi M, Wang W, Duchen MR, Patani R, Zammit PS, Wells DJ, Eschenhagen T, Tedesco FS. Maffioletti SM, et al. Among authors: patani r. Cell Rep. 2018 Apr 17;23(3):899-908. doi: 10.1016/j.celrep.2018.03.091. Cell Rep. 2018. PMID: 29669293 Free PMC article.
Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS.
Luisier R, Tyzack GE, Hall CE, Mitchell JS, Devine H, Taha DM, Malik B, Meyer I, Greensmith L, Newcombe J, Ule J, Luscombe NM, Patani R. Luisier R, et al. Among authors: patani r. Nat Commun. 2018 May 22;9(1):2010. doi: 10.1038/s41467-018-04373-8. Nat Commun. 2018. PMID: 29789581 Free PMC article.
Delineating Astrocytic Cytokine Responses in a Human Stem Cell Model of Neural Trauma.
Thelin EP, Hall CE, Tyzack GE, Frostell A, Giorgi-Coll S, Alam A, Carpenter KLH, Mitchell J, Tajsic T, Hutchinson PJ, Patani R, Helmy A. Thelin EP, et al. Among authors: patani r. J Neurotrauma. 2020 Jan 1;37(1):93-105. doi: 10.1089/neu.2019.6480. Epub 2019 Sep 18. J Neurotrauma. 2020. PMID: 31452443 Free PMC article.
93 results