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α-Synuclein antisense oligonucleotides as a disease-modifying therapy for Parkinson's disease.
Cole TA, Zhao H, Collier TJ, Sandoval I, Sortwell CE, Steece-Collier K, Daley BF, Booms A, Lipton J, Welch M, Berman M, Jandreski L, Graham D, Weihofen A, Celano S, Schulz E, Cole-Strauss A, Luna E, Quach D, Mohan A, Bennett CF, Swayze EE, Kordasiewicz HB, Luk KC, Paumier KL. Cole TA, et al. Among authors: schulz e. JCI Insight. 2021 Mar 8;6(5):e135633. doi: 10.1172/jci.insight.135633. JCI Insight. 2021. PMID: 33682798 Free PMC article.
Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration.
Paumier KL, Luk KC, Manfredsson FP, Kanaan NM, Lipton JW, Collier TJ, Steece-Collier K, Kemp CJ, Celano S, Schulz E, Sandoval IM, Fleming S, Dirr E, Polinski NK, Trojanowski JQ, Lee VM, Sortwell CE. Paumier KL, et al. Among authors: schulz e. Neurobiol Dis. 2015 Oct;82:185-199. doi: 10.1016/j.nbd.2015.06.003. Epub 2015 Jun 17. Neurobiol Dis. 2015. PMID: 26093169 Free PMC article.
Mitochondrial pyruvate carrier regulates autophagy, inflammation, and neurodegeneration in experimental models of Parkinson's disease.
Ghosh A, Tyson T, George S, Hildebrandt EN, Steiner JA, Madaj Z, Schulz E, Machiela E, McDonald WG, Escobar Galvis ML, Kordower JH, Van Raamsdonk JM, Colca JR, Brundin P. Ghosh A, et al. Among authors: schulz e. Sci Transl Med. 2016 Dec 7;8(368):368ra174. doi: 10.1126/scitranslmed.aag2210. Sci Transl Med. 2016. PMID: 27928028
Biochemical Profiling of the Brain and Blood Metabolome in a Mouse Model of Prodromal Parkinson's Disease Reveals Distinct Metabolic Profiles.
Graham SF, Rey NL, Yilmaz A, Kumar P, Madaj Z, Maddens M, Bahado-Singh RO, Becker K, Schulz E, Meyerdirk LK, Steiner JA, Ma J, Brundin P. Graham SF, et al. Among authors: schulz e. J Proteome Res. 2018 Jul 6;17(7):2460-2469. doi: 10.1021/acs.jproteome.8b00224. Epub 2018 May 25. J Proteome Res. 2018. PMID: 29762036 Free PMC article.
T Cells Limit Accumulation of Aggregate Pathology Following Intrastriatal Injection of α-Synuclein Fibrils.
George S, Tyson T, Rey NL, Sheridan R, Peelaerts W, Becker K, Schulz E, Meyerdirk L, Burmeister AR, von Linstow CU, Steiner JA, Galvis MLE, Ma J, Pospisilik JA, Labrie V, Brundin L, Brundin P. George S, et al. Among authors: schulz e. J Parkinsons Dis. 2021;11(2):585-603. doi: 10.3233/JPD-202351. J Parkinsons Dis. 2021. PMID: 33579871 Free PMC article.
Air pollution nanoparticle and alpha-synuclein fibrils synergistically decrease glutamate receptor A1, depending upon nPM batch activity.
Zhang H, D'Agostino C, Tulisiak C, Thorwald MA, Bergkvist L, Lindquist A, Meyerdirk L, Schulz E, Becker K, Steiner JA, Cacciottolo M, Kwatra M, Rey NL, Escobar Galvis ML, Ma J, Sioutas C, Morgan TE, Finch CE, Brundin P. Zhang H, et al. Among authors: schulz e. Heliyon. 2023 Apr 19;9(4):e15622. doi: 10.1016/j.heliyon.2023.e15622. eCollection 2023 Apr. Heliyon. 2023. PMID: 37128335 Free PMC article.
1,066 results