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Structural basis for inhibition of the SARS-CoV-2 RNA polymerase by suramin.
Yin W, Luan X, Li Z, Zhou Z, Wang Q, Gao M, Wang X, Zhou F, Shi J, You E, Liu M, Wang Q, Jiang Y, Jiang H, Xiao G, Zhang L, Yu X, Zhang S, Eric Xu H. Yin W, et al. Among authors: jiang h, jiang y. Nat Struct Mol Biol. 2021 Mar;28(3):319-325. doi: 10.1038/s41594-021-00570-0. Epub 2021 Mar 5. Nat Struct Mol Biol. 2021. PMID: 33674802
EZH2: biology, disease, and structure-based drug discovery.
Tan JZ, Yan Y, Wang XX, Jiang Y, Xu HE. Tan JZ, et al. Among authors: jiang y. Acta Pharmacol Sin. 2014 Feb;35(2):161-74. doi: 10.1038/aps.2013.161. Epub 2013 Dec 23. Acta Pharmacol Sin. 2014. PMID: 24362326 Free PMC article. Review.
Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser.
Kang Y, Zhou XE, Gao X, He Y, Liu W, Ishchenko A, Barty A, White TA, Yefanov O, Han GW, Xu Q, de Waal PW, Ke J, Tan MH, Zhang C, Moeller A, West GM, Pascal BD, Van Eps N, Caro LN, Vishnivetskiy SA, Lee RJ, Suino-Powell KM, Gu X, Pal K, Ma J, Zhi X, Boutet S, Williams GJ, Messerschmidt M, Gati C, Zatsepin NA, Wang D, James D, Basu S, Roy-Chowdhury S, Conrad CE, Coe J, Liu H, Lisova S, Kupitz C, Grotjohann I, Fromme R, Jiang Y, Tan M, Yang H, Li J, Wang M, Zheng Z, Li D, Howe N, Zhao Y, Standfuss J, Diederichs K, Dong Y, Potter CS, Carragher B, Caffrey M, Jiang H, Chapman HN, Spence JC, Fromme P, Weierstall U, Ernst OP, Katritch V, Gurevich VV, Griffin PR, Hubbell WL, Stevens RC, Cherezov V, Melcher K, Xu HE. Kang Y, et al. Among authors: jiang h, jiang y. Nature. 2015 Jul 30;523(7562):561-7. doi: 10.1038/nature14656. Epub 2015 Jul 22. Nature. 2015. PMID: 26200343 Free PMC article.
Structure of the PRC2 complex and application to drug discovery.
Shi Y, Wang XX, Zhuang YW, Jiang Y, Melcher K, Xu HE. Shi Y, et al. Among authors: jiang y. Acta Pharmacol Sin. 2017 Jul;38(7):963-976. doi: 10.1038/aps.2017.7. Epub 2017 Apr 17. Acta Pharmacol Sin. 2017. PMID: 28414199 Free PMC article. Review.
Crystal structure of the human 5-HT1B serotonin receptor bound to an inverse agonist.
Yin W, Zhou XE, Yang D, de Waal PW, Wang M, Dai A, Cai X, Huang CY, Liu P, Wang X, Yin Y, Liu B, Zhou Y, Wang J, Liu H, Caffrey M, Melcher K, Xu Y, Wang MW, Xu HE, Jiang Y. Yin W, et al. Among authors: jiang y. Cell Discov. 2018 Mar 13;4:12. doi: 10.1038/s41421-018-0009-2. eCollection 2018. Cell Discov. 2018. PMID: 29560272 Free PMC article.
Cryo-EM structure of human rhodopsin bound to an inhibitory G protein.
Kang Y, Kuybeda O, de Waal PW, Mukherjee S, Van Eps N, Dutka P, Zhou XE, Bartesaghi A, Erramilli S, Morizumi T, Gu X, Yin Y, Liu P, Jiang Y, Meng X, Zhao G, Melcher K, Ernst OP, Kossiakoff AA, Subramaniam S, Xu HE. Kang Y, et al. Among authors: jiang y. Nature. 2018 Jun;558(7711):553-558. doi: 10.1038/s41586-018-0215-y. Epub 2018 Jun 13. Nature. 2018. PMID: 29899450 Free PMC article.
A complex structure of arrestin-2 bound to a G protein-coupled receptor.
Yin W, Li Z, Jin M, Yin YL, de Waal PW, Pal K, Yin Y, Gao X, He Y, Gao J, Wang X, Zhang Y, Zhou H, Melcher K, Jiang Y, Cong Y, Edward Zhou X, Yu X, Eric Xu H. Yin W, et al. Among authors: jiang y. Cell Res. 2019 Dec;29(12):971-983. doi: 10.1038/s41422-019-0256-2. Epub 2019 Nov 27. Cell Res. 2019. PMID: 31776446 Free PMC article.
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