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Loss of fibronectin from the aged stem cell niche affects the regenerative capacity of skeletal muscle in mice.
Lukjanenko L, Jung MJ, Hegde N, Perruisseau-Carrier C, Migliavacca E, Rozo M, Karaz S, Jacot G, Schmidt M, Li L, Metairon S, Raymond F, Lee U, Sizzano F, Wilson DH, Dumont NA, Palini A, Fässler R, Steiner P, Descombes P, Rudnicki MA, Fan CM, von Maltzahn J, Feige JN, Bentzinger CF. Lukjanenko L, et al. Among authors: feige jn. Nat Med. 2016 Aug;22(8):897-905. doi: 10.1038/nm.4126. Epub 2016 Jul 4. Nat Med. 2016. PMID: 27376579 Free PMC article.
Aging Disrupts Muscle Stem Cell Function by Impairing Matricellular WISP1 Secretion from Fibro-Adipogenic Progenitors.
Lukjanenko L, Karaz S, Stuelsatz P, Gurriaran-Rodriguez U, Michaud J, Dammone G, Sizzano F, Mashinchian O, Ancel S, Migliavacca E, Liot S, Jacot G, Metairon S, Raymond F, Descombes P, Palini A, Chazaud B, Rudnicki MA, Bentzinger CF, Feige JN. Lukjanenko L, et al. Among authors: feige jn. Cell Stem Cell. 2019 Mar 7;24(3):433-446.e7. doi: 10.1016/j.stem.2018.12.014. Epub 2019 Jan 24. Cell Stem Cell. 2019. PMID: 30686765 Free PMC article.
Adipogenic progenitors keep muscle stem cells young.
Ancel S, Mashinchian O, Feige JN. Ancel S, et al. Among authors: feige jn. Aging (Albany NY). 2019 Sep 19;11(18):7331-7333. doi: 10.18632/aging.102304. Epub 2019 Sep 19. Aging (Albany NY). 2019. PMID: 31537755 Free PMC article. No abstract available.
In vivo transcriptomic profiling using cell encapsulation identifies effector pathways of systemic aging.
Mashinchian O, Hong X, Michaud J, Migliavacca E, Lefebvre G, Boss C, De Franceschi F, Le Moal E, Collerette-Tremblay J, Isern J, Metairon S, Raymond F, Descombes P, Bouche N, Muñoz-Cánoves P, Feige JN, Bentzinger CF. Mashinchian O, et al. Among authors: feige jn. Elife. 2022 Mar 4;11:e57393. doi: 10.7554/eLife.57393. Elife. 2022. PMID: 35245177 Free PMC article.
An engineered multicellular stem cell niche for the 3D derivation of human myogenic progenitors from iPSCs.
Mashinchian O, De Franceschi F, Nassiri S, Michaud J, Migliavacca E, Aouad P, Metairon S, Pruvost S, Karaz S, Fabre P, Molina T, Stuelsatz P, Hegde N, Le Moal E, Dammone G, Dumont NA, Lutolf MP, Feige JN, Bentzinger CF. Mashinchian O, et al. Among authors: feige jn. EMBO J. 2022 Jul 18;41(14):e110655. doi: 10.15252/embj.2022110655. Epub 2022 Jun 15. EMBO J. 2022. PMID: 35703167 Free PMC article.
Nicotinamide riboside kinases regulate skeletal muscle fiber-type specification and are rate-limiting for metabolic adaptations during regeneration.
Sonntag T, Ancel S, Karaz S, Cichosz P, Jacot G, Giner MP, Sanchez-Garcia JL, Pannérec A, Moco S, Sorrentino V, Cantó C, Feige JN. Sonntag T, et al. Among authors: feige jn. Front Cell Dev Biol. 2022 Nov 9;10:1049653. doi: 10.3389/fcell.2022.1049653. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 36438552 Free PMC article.
Young extracellular vesicles rejuvenate aged muscle.
Ancel S, Feige JN. Ancel S, et al. Among authors: feige jn. Nat Aging. 2021 Dec;1(12):1078-1080. doi: 10.1038/s43587-021-00153-0. Nat Aging. 2021. PMID: 37117521 No abstract available.
63 results