García-Gutiérrez L - Search Results

1

IQGAP1 Is a Scaffold of the Core Proteins of the Hippo Pathway and Negatively Regulates the Pro-Apoptotic Signal Mediated by This Pathway.

Quinn NP, García-Gutiérrez L, Doherty C, von Kriegsheim A, Fallahi E, Sacks DB, Matallanas D. Quinn NP, et al. Among authors: garcia gutierrez l. Cells. 2021 Feb 23;10(2):478. doi: 10.3390/cells10020478. Cells. 2021. PMID: 33672268 Free PMC article.

2

Interaction of LATS1 with SMAC links the MST2/Hippo pathway with apoptosis in an IAP-dependent manner.

García-Gutiérrez L, Fallahi E, Aboud N, Quinn N, Matallanas D. García-Gutiérrez L, et al. Cell Death Dis. 2022 Aug 8;13(8):692. doi: 10.1038/s41419-022-05147-3. Cell Death Dis. 2022. PMID: 35941108 Free PMC article.

3

RASSF1A Tumour Suppressor: Target the Network for Effective Cancer Therapy.

García-Gutiérrez L, McKenna S, Kolch W, Matallanas D. García-Gutiérrez L, et al. Cancers (Basel). 2020 Jan 17;12(1):229. doi: 10.3390/cancers12010229. Cancers (Basel). 2020. PMID: 31963420 Free PMC article. Review.

4

BAX and SMAC regulate bistable properties of the apoptotic caspase system.

McKenna S, García-Gutiérrez L, Matallanas D, Fey D. McKenna S, et al. Among authors: garcia gutierrez l. Sci Rep. 2021 Feb 8;11(1):3272. doi: 10.1038/s41598-021-82215-2. Sci Rep. 2021. PMID: 33558564 Free PMC article.

5

Proteasomal down-regulation of the proapoptotic MST2 pathway contributes to BRAF inhibitor resistance in melanoma.

Romano D, García-Gutiérrez L, Aboud N, Duffy DJ, Flaherty KT, Frederick DT, Kolch W, Matallanas D. Romano D, et al. Among authors: garcia gutierrez l. Life Sci Alliance. 2022 Aug 29;5(10):e202201445. doi: 10.26508/lsa.202201445. Print 2022 Oct. Life Sci Alliance. 2022. PMID: 36038253 Free PMC article.

6

Resistance to Targeted Therapy and RASSF1A Loss in Melanoma: What Are We Missing?

McKenna S, García-Gutiérrez L. McKenna S, et al. Among authors: garcia gutierrez l. Int J Mol Sci. 2021 May 12;22(10):5115. doi: 10.3390/ijms22105115. Int J Mol Sci. 2021. PMID: 34066022 Free PMC article. Review.

7

Myc stimulates cell cycle progression through the activation of Cdk1 and phosphorylation of p27.

García-Gutiérrez L, Bretones G, Molina E, Arechaga I, Symonds C, Acosta JC, Blanco R, Fernández A, Alonso L, Sicinski P, Barbacid M, Santamaría D, León J. García-Gutiérrez L, et al. Sci Rep. 2019 Dec 10;9(1):18693. doi: 10.1038/s41598-019-54917-1. Sci Rep. 2019. PMID: 31822694 Free PMC article.

8

MYC Oncogene Contributions to Release of Cell Cycle Brakes.

García-Gutiérrez L, Delgado MD, León J. García-Gutiérrez L, et al. Genes (Basel). 2019 Mar 22;10(3):244. doi: 10.3390/genes10030244. Genes (Basel). 2019. PMID: 30909496 Free PMC article. Review.

9

p21 as a transcriptional co-repressor of S-phase and mitotic control genes.

Ferrándiz N, Caraballo JM, García-Gutierrez L, Devgan V, Rodriguez-Paredes M, Lafita MC, Bretones G, Quintanilla A, Muñoz-Alonso MJ, Blanco R, Reyes JC, Agell N, Delgado MD, Dotto GP, León J. Ferrándiz N, et al. PLoS One. 2012;7(5):e37759. doi: 10.1371/journal.pone.0037759. Epub 2012 May 25. PLoS One. 2012. PMID: 22662213 Free PMC article.

10

Sin3b interacts with Myc and decreases Myc levels.

Garcia-Sanz P, Quintanilla A, Lafita MC, Moreno-Bueno G, García-Gutierrez L, Tabor V, Varela I, Shiio Y, Larsson LG, Portillo F, Leon J. Garcia-Sanz P, et al. J Biol Chem. 2014 Aug 8;289(32):22221-36. doi: 10.1074/jbc.M113.538744. Epub 2014 Jun 20. J Biol Chem. 2014. PMID: 24951594 Free PMC article.

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