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Synthesis and Biological Evaluation of 1-(Diarylmethyl)-1H-1,2,4-triazoles and 1-(Diarylmethyl)-1H-imidazoles as a Novel Class of Anti-Mitotic Agent for Activity in Breast Cancer.
Ana G, Kelly PM, Malebari AM, Noorani S, Nathwani SM, Twamley B, Fayne D, O'Boyle NM, Zisterer DM, Pimentel EF, Endringer DC, Meegan MJ. Ana G, et al. Among authors: nathwani sm. Pharmaceuticals (Basel). 2021 Feb 22;14(2):169. doi: 10.3390/ph14020169. Pharmaceuticals (Basel). 2021. PMID: 33671674 Free PMC article.
The vascular targeting agent combretastatin-A4 and a novel cis-Restricted {beta}-Lactam Analogue, CA-432, induce apoptosis in human chronic myeloid leukemia cells and ex vivo patient samples including those displaying multidrug resistance.
Greene LM, Nathwani SM, Bright SA, Fayne D, Croke A, Gagliardi M, McElligott AM, O'Connor L, Carr M, Keely NO, O'Boyle NM, Carroll P, Sarkadi B, Conneally E, Lloyd DG, Lawler M, Meegan MJ, Zisterer DM. Greene LM, et al. Among authors: nathwani sm. J Pharmacol Exp Ther. 2010 Nov;335(2):302-13. doi: 10.1124/jpet.110.170415. Epub 2010 Aug 10. J Pharmacol Exp Ther. 2010. PMID: 20699436
Antitumor effect of pyrrolo-1,5-benzoxazepine-15 and its synergistic effect with Oxaliplatin and 5-FU in colorectal cancer cells.
Fiore D, Proto MC, Pisanti S, Picardi P, Pagano Zottola AC, Butini S, Gemma S, Casagni A, Laezza C, Vitale M, Ligresti A, Di Marzo V, Zisterer DM, Nathwani S, Williams DC, Campiani G, Gazzerro P, Bifulco M. Fiore D, et al. Cancer Biol Ther. 2016 Aug 2;17(8):849-58. doi: 10.1080/15384047.2015.1078028. Cancer Biol Ther. 2016. PMID: 26392056 Free PMC article.
Development of novel cyclic peptides as pro-apoptotic agents.
Brindisi M, Maramai S, Brogi S, Fanigliulo E, Butini S, Guarino E, Casagni A, Lamponi S, Bonechi C, Nathwani SM, Finetti F, Ragonese F, Arcidiacono P, Campiglia P, Valenti S, Novellino E, Spaccapelo R, Morbidelli L, Zisterer DM, Williams CD, Donati A, Baldari C, Campiani G, Ulivieri C, Gemma S. Brindisi M, et al. Among authors: nathwani sm. Eur J Med Chem. 2016 Jul 19;117:301-20. doi: 10.1016/j.ejmech.2016.04.001. Epub 2016 Apr 5. Eur J Med Chem. 2016. PMID: 27150036
27 results