Childs RW - Search Results

1

Systematic improvements in lentiviral transduction of primary human natural killer cells undergoing ex vivo expansion.

Allan DSJ, Chakraborty M, Waller GC, Hochman MJ, Poolcharoen A, Reger RN, Childs RW. Allan DSJ, et al. Among authors: childs rw. Mol Ther Methods Clin Dev. 2021 Jan 20;20:559-571. doi: 10.1016/j.omtm.2021.01.008. eCollection 2021 Mar 12. Mol Ther Methods Clin Dev. 2021. PMID: 33665226 Free PMC article.

2

Efficient mRNA-Based Genetic Engineering of Human NK Cells with High-Affinity CD16 and CCR7 Augments Rituximab-Induced ADCC against Lymphoma and Targets NK Cell Migration toward the Lymph Node-Associated Chemokine CCL19.

Carlsten M, Levy E, Karambelkar A, Li L, Reger R, Berg M, Peshwa MV, Childs RW. Carlsten M, et al. Among authors: childs rw. Front Immunol. 2016 Mar 22;7:105. doi: 10.3389/fimmu.2016.00105. eCollection 2016. Front Immunol. 2016. PMID: 27047492 Free PMC article.

3

Checkpoint Inhibition of KIR2D with the Monoclonal Antibody IPH2101 Induces Contraction and Hyporesponsiveness of NK Cells in Patients with Myeloma.

Carlsten M, Korde N, Kotecha R, Reger R, Bor S, Kazandjian D, Landgren O, Childs RW. Carlsten M, et al. Among authors: childs rw. Clin Cancer Res. 2016 Nov 1;22(21):5211-5222. doi: 10.1158/1078-0432.CCR-16-1108. Epub 2016 Jun 15. Clin Cancer Res. 2016. PMID: 27307594 Free PMC article. Clinical Trial.

4

Effect of high-dose plerixafor on CD34⁺ cell mobilization in healthy stem cell donors: results of a randomized crossover trial.

Pantin J, Purev E, Tian X, Cook L, Donohue-Jerussi T, Cho E, Reger R, Hsieh M, Khuu H, Calandra G, Geller NL, Childs RW. Pantin J, et al. Among authors: childs rw. Haematologica. 2017 Mar;102(3):600-609. doi: 10.3324/haematol.2016.147132. Epub 2016 Oct 20. Haematologica. 2017. PMID: 27846612 Free PMC article. Clinical Trial.

5

Allogeneic transplantation using CD34⁺ selected peripheral blood progenitor cells combined with non-mobilized donor T cells for refractory severe aplastic anaemia.

Purev E, Tian X, Aue G, Pantin J, Vo P, Shalabi R, Reger RN, Cook L, Ramos C, Cho E, Worthy T, Khuu H, Stroncek D, Young NS, Childs RW. Purev E, et al. Among authors: childs rw. Br J Haematol. 2017 Mar;176(6):950-960. doi: 10.1111/bjh.14448. Epub 2017 Feb 7. Br J Haematol. 2017. PMID: 28169418 Free PMC article. Clinical Trial.

6

Transcriptome analysis reveals similarities between human blood CD3^- CD56^bright cells and mouse CD127⁺ innate lymphoid cells.

Allan DSJ, Cerdeira AS, Ranjan A, Kirkham CL, Aguilar OA, Tanaka M, Childs RW, Dunbar CE, Strominger JL, Kopcow HD, Carlyle JR. Allan DSJ, et al. Among authors: childs rw. Sci Rep. 2017 Jun 14;7(1):3501. doi: 10.1038/s41598-017-03256-0. Sci Rep. 2017. PMID: 28615725 Free PMC article.

7

Bortezomib sensitizes multiple myeloma to NK cells via ER-stress-induced suppression of HLA-E and upregulation of DR5.

Carlsten M, Namazi A, Reger R, Levy E, Berg M, St Hilaire C, Childs RW. Carlsten M, et al. Among authors: childs rw. Oncoimmunology. 2018 Nov 2;8(2):e1534664. doi: 10.1080/2162402X.2018.1534664. eCollection 2019. Oncoimmunology. 2018. PMID: 30713790 Free PMC article.

8

In Vivo Tracking of Adoptively Transferred Natural Killer Cells in Rhesus Macaques Using ⁸⁹Zirconium-Oxine Cell Labeling and PET Imaging.

Sato N, Stringaris K, Davidson-Moncada JK, Reger R, Adler SS, Dunbar C, Choyke PL, Childs RW. Sato N, et al. Among authors: childs rw. Clin Cancer Res. 2020 Jun 1;26(11):2573-2581. doi: 10.1158/1078-0432.CCR-19-2897. Epub 2020 Feb 7. Clin Cancer Res. 2020. PMID: 32034075 Free PMC article.

9

Augmentation of NK Cell Proliferation and Anti-tumor Immunity by Transgenic Expression of Receptors for EPO or TPO.

Chanswangphuwana C, Allan DSJ, Chakraborty M, Reger RN, Childs RW. Chanswangphuwana C, et al. Among authors: childs rw. Mol Ther. 2021 Jan 6;29(1):47-59. doi: 10.1016/j.ymthe.2020.09.023. Epub 2020 Sep 20. Mol Ther. 2021. PMID: 33010232 Free PMC article.

10

Genome-Wide Analysis of Off-Target CRISPR/Cas9 Activity in Single-Cell-Derived Human Hematopoietic Stem and Progenitor Cell Clones.

Smith RH, Chen YC, Seifuddin F, Hupalo D, Alba C, Reger R, Tian X, Araki D, Dalgard CL, Childs RW, Pirooznia M, Larochelle A. Smith RH, et al. Among authors: childs rw. Genes (Basel). 2020 Dec 13;11(12):1501. doi: 10.3390/genes11121501. Genes (Basel). 2020. PMID: 33322084 Free PMC article. Clinical Trial.

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