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WNT inhibition creates a BRCA-like state in Wnt-addicted cancer.
Kaur A, Lim JYS, Sepramaniam S, Patnaik S, Harmston N, Lee MA, Petretto E, Virshup DM, Madan B. Kaur A, et al. Among authors: harmston n. EMBO Mol Med. 2021 Apr 9;13(4):e13349. doi: 10.15252/emmm.202013349. Epub 2021 Mar 4. EMBO Mol Med. 2021. PMID: 33660437 Free PMC article.
Wnt addiction of genetically defined cancers reversed by PORCN inhibition.
Madan B, Ke Z, Harmston N, Ho SY, Frois AO, Alam J, Jeyaraj DA, Pendharkar V, Ghosh K, Virshup IH, Manoharan V, Ong EH, Sangthongpitag K, Hill J, Petretto E, Keller TH, Lee MA, Matter A, Virshup DM. Madan B, et al. Among authors: harmston n. Oncogene. 2016 Apr 28;35(17):2197-207. doi: 10.1038/onc.2015.280. Epub 2015 Aug 10. Oncogene. 2016. PMID: 26257057 Free PMC article.
Wnt proteins synergize to activate β-catenin signaling.
Alok A, Lei Z, Jagannathan NS, Kaur S, Harmston N, Rozen SG, Tucker-Kellogg L, Virshup DM. Alok A, et al. Among authors: harmston n. J Cell Sci. 2017 May 1;130(9):1532-1544. doi: 10.1242/jcs.198093. Epub 2017 Mar 13. J Cell Sci. 2017. PMID: 28289266
Changes in macrophage transcriptome associate with systemic sclerosis and mediate GSDMA contribution to disease risk.
Moreno-Moral A, Bagnati M, Koturan S, Ko JH, Fonseca C, Harmston N, Game L, Martin J, Ong V, Abraham DJ, Denton CP, Behmoaras J, Petretto E. Moreno-Moral A, et al. Among authors: harmston n. Ann Rheum Dis. 2018 Apr;77(4):596-601. doi: 10.1136/annrheumdis-2017-212454. Epub 2018 Jan 17. Ann Rheum Dis. 2018. PMID: 29348297 Free PMC article.
38 results