Falk MJ - Search Results

1

Combinatorial glucose, nicotinic acid and N-acetylcysteine therapy has synergistic effect in preclinical C. elegans and zebrafish models of mitochondrial complex I disease.

Guha S, Mathew ND, Konkwo C, Ostrovsky J, Kwon YJ, Polyak E, Seiler C, Bennett M, Xiao R, Zhang Z, Nakamaru-Ogiso E, Falk MJ. Guha S, et al. Among authors: falk mj. Hum Mol Genet. 2021 May 12;30(7):536-551. doi: 10.1093/hmg/ddab059. Hum Mol Genet. 2021. PMID: 33640978 Free PMC article.

2

Metabolic pathway profiling of mitochondrial respiratory chain mutants in C. elegans.

Falk MJ, Zhang Z, Rosenjack JR, Nissim I, Daikhin E, Nissim I, Sedensky MM, Yudkoff M, Morgan PG. Falk MJ, et al. Mol Genet Metab. 2008 Apr;93(4):388-97. doi: 10.1016/j.ymgme.2007.11.007. Epub 2008 Feb 21. Mol Genet Metab. 2008. PMID: 18178500 Free PMC article.

3

Primary coenzyme Q deficiency in Pdss2 mutant mice causes isolated renal disease.

Peng M, Falk MJ, Haase VH, King R, Polyak E, Selak M, Yudkoff M, Hancock WW, Meade R, Saiki R, Lunceford AL, Clarke CF, Gasser DL. Peng M, et al. Among authors: falk mj. PLoS Genet. 2008 Apr 25;4(4):e1000061. doi: 10.1371/journal.pgen.1000061. PLoS Genet. 2008. PMID: 18437205 Free PMC article.

4

Subcomplex Ilambda specifically controls integrated mitochondrial functions in Caenorhabditis elegans.

Falk MJ, Rosenjack JR, Polyak E, Suthammarak W, Chen Z, Morgan PG, Sedensky MM. Falk MJ, et al. PLoS One. 2009 Aug 12;4(8):e6607. doi: 10.1371/journal.pone.0006607. PLoS One. 2009. PMID: 19672299 Free PMC article.

5

Mitochondrial respiratory chain dysfunction variably increases oxidant stress in Caenorhabditis elegans.

Dingley S, Polyak E, Lightfoot R, Ostrovsky J, Rao M, Greco T, Ischiropoulos H, Falk MJ. Dingley S, et al. Among authors: falk mj. Mitochondrion. 2010 Mar;10(2):125-36. doi: 10.1016/j.mito.2009.11.003. Epub 2009 Nov 10. Mitochondrion. 2010. PMID: 19900588 Free PMC article.

6

Cross-platform expression microarray performance in a mouse model of mitochondrial disease therapy.

Zhang Z, Gasser DL, Rappaport EF, Falk MJ. Zhang Z, et al. Among authors: falk mj. Mol Genet Metab. 2010 Mar;99(3):309-18. doi: 10.1016/j.ymgme.2009.10.179. Epub 2009 Oct 30. Mol Genet Metab. 2010. PMID: 19944634 Free PMC article.

7

Leucine-rich pentatricopeptide-repeat containing protein regulates mitochondrial transcription.

Sondheimer N, Fang JK, Polyak E, Falk MJ, Avadhani NG. Sondheimer N, et al. Among authors: falk mj. Biochemistry. 2010 Sep 7;49(35):7467-73. doi: 10.1021/bi1008479. Biochemistry. 2010. PMID: 20677761 Free PMC article.

8

Bacteria, yeast, worms, and flies: exploiting simple model organisms to investigate human mitochondrial diseases.

Rea SL, Graham BH, Nakamaru-Ogiso E, Kar A, Falk MJ. Rea SL, et al. Among authors: falk mj. Dev Disabil Res Rev. 2010;16(2):200-18. doi: 10.1002/ddrr.114. Dev Disabil Res Rev. 2010. PMID: 20818735 Free PMC article. Review.

9

Stable isotopic profiling of intermediary metabolic flux in developing and adult stage Caenorhabditis elegans.

Falk MJ, Rao M, Ostrovsky J, Daikhin E, Nissim I, Yudkoff M. Falk MJ, et al. J Vis Exp. 2011 Feb 27;(48):2288. doi: 10.3791/2288. J Vis Exp. 2011. PMID: 21403629 Free PMC article.

10

Probucol ameliorates renal and metabolic sequelae of primary CoQ deficiency in Pdss2 mutant mice.

Falk MJ, Polyak E, Zhang Z, Peng M, King R, Maltzman JS, Okwuego E, Horyn O, Nakamaru-Ogiso E, Ostrovsky J, Xie LX, Chen JY, Marbois B, Nissim I, Clarke CF, Gasser DL. Falk MJ, et al. EMBO Mol Med. 2011 Jul;3(7):410-27. doi: 10.1002/emmm.201100149. Epub 2011 Jun 8. EMBO Mol Med. 2011. PMID: 21567994 Free PMC article.

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