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Detection of gene fusions using targeted next-generation sequencing: a comparative evaluation.
Heydt C, Wölwer CB, Velazquez Camacho O, Wagener-Ryczek S, Pappesch R, Siemanowski J, Rehker J, Haller F, Agaimy A, Worm K, Herold T, Pfarr N, Weichert W, Kirchner T, Jung A, Kumbrink J, Goering W, Esposito I, Buettner R, Hillmer AM, Merkelbach-Bruse S. Heydt C, et al. Among authors: kumbrink j. BMC Med Genomics. 2021 Feb 27;14(1):62. doi: 10.1186/s12920-021-00909-y. BMC Med Genomics. 2021. PMID: 33639937 Free PMC article.
Mitochondrial Dynamics in Tachycardiomyopathy.
Heinzmann D, Klingel K, Müller K, Kumbrink J, Kirchner T, Schreieck J, Gawaz M, Seizer P. Heinzmann D, et al. Among authors: kumbrink j. Cell Physiol Biochem. 2019;52(3):435-438. doi: 10.33594/000000031. Epub 2019 Mar 15. Cell Physiol Biochem. 2019. PMID: 30873819 Free article.
Testing NTRK testing: Wet-lab and in silico comparison of RNA-based targeted sequencing assays.
Pfarr N, Kirchner M, Lehmann U, Leichsenring J, Merkelbach-Bruse S, Glade J, Hummel M, Stögbauer F, Lehmann A, Trautmann M, Kumbrink J, Jung A, Dietmaier W, Endris V, Kazdal D, Evert M, Horst D, Kreipe H, Kirchner T, Wardelmann E, Lassen U, Büttner R, Weichert W, Dietel M, Schirmacher P, Stenzinger A. Pfarr N, et al. Among authors: kumbrink j. Genes Chromosomes Cancer. 2020 Mar;59(3):178-188. doi: 10.1002/gcc.22819. Epub 2019 Nov 18. Genes Chromosomes Cancer. 2020. PMID: 31652375
Therapeutic management of neuro-oncologic patients - potential relevance of CSF liquid biopsy.
von Baumgarten L, Kumbrink J, Jung A, Reischer A, Flach M, Liebmann S, Metzeler KH, Holch JW, Niyazi M, Thon N, Straube A, von Bergwelt-Baildon M, Heinemann V, Kirchner T, Westphalen CB. von Baumgarten L, et al. Among authors: kumbrink j. Theranostics. 2020 Jan 1;10(2):856-866. doi: 10.7150/thno.36884. eCollection 2020. Theranostics. 2020. PMID: 31903155 Free PMC article.
NTRK testing: First results of the QuiP-EQA scheme and a comprehensive map of NTRK fusion variants and their diagnostic coverage by targeted RNA-based NGS assays.
Kirchner M, Glade J, Lehmann U, Merkelbach-Bruse S, Hummel M, Lehmann A, Trautmann M, Kumbrink J, Jung A, Dietmaier W, Endris V, Kazdal D, Ploeger C, Evert M, Horst D, Kreipe H, Kirchner T, Wardelmann E, Büttner R, Weichert W, Dietel M, Schirmacher P, Stenzinger A, Pfarr N. Kirchner M, et al. Among authors: kumbrink j. Genes Chromosomes Cancer. 2020 Aug;59(8):445-453. doi: 10.1002/gcc.22853. Epub 2020 May 9. Genes Chromosomes Cancer. 2020. PMID: 32319699
Mixed large cell neuroendocrine carcinoma and squamous cell carcinoma of the colon: detailed molecular characterisation of two cases indicates a distinct colorectal cancer entity.
Woischke C, Jung P, Jung A, Kumbrink J, Eisenlohr S, Auernhammer CJ, Vieth M, Kirchner T, Neumann J. Woischke C, et al. Among authors: kumbrink j. J Pathol Clin Res. 2021 Jan;7(1):75-85. doi: 10.1002/cjp2.183. Epub 2020 Nov 16. J Pathol Clin Res. 2021. PMID: 33197299 Free PMC article.
Consensus molecular subtypes in metastatic colorectal cancer treated with sequential versus combined fluoropyrimidine, bevacizumab and irinotecan (XELAVIRI trial).
Stahler A, Heinemann V, Schuster V, Heinrich K, Kurreck A, Gießen-Jung C, Fischer von Weikersthal L, Kaiser F, Decker T, Held S, Graeven U, Schwaner I, Denzlinger C, Schenk M, Neumann J, Kirchner T, Jung A, Kumbrink J, Stintzing S, Modest DP. Stahler A, et al. Among authors: kumbrink j. Eur J Cancer. 2021 Nov;157:71-80. doi: 10.1016/j.ejca.2021.08.017. Epub 2021 Sep 8. Eur J Cancer. 2021. PMID: 34507244 Clinical Trial.
Disease Modeling on Tumor Organoids Implicates AURKA as a Therapeutic Target in Liver Metastatic Colorectal Cancer.
Boos SL, Loevenich LP, Vosberg S, Engleitner T, Öllinger R, Kumbrink J, Rokavec M, Michl M, Greif PA, Jung A, Hermeking H, Neumann J, Kirchner T, Rad R, Jung P. Boos SL, et al. Among authors: kumbrink j. Cell Mol Gastroenterol Hepatol. 2022;13(2):517-540. doi: 10.1016/j.jcmgh.2021.10.008. Epub 2021 Oct 23. Cell Mol Gastroenterol Hepatol. 2022. PMID: 34700030 Free PMC article.
61 results