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Mechanochemical control of epidermal stem cell divisions by B-plexins.
Jiang C, Javed A, Kaiser L, Nava MM, Xu R, Brandt DT, Zhao D, Mayer B, Fernández-Baldovinos J, Zhou L, Höß C, Sawmynaden K, Oleksy A, Matthews D, Weinstein LS, Hahn H, Gröne HJ, Graumann PL, Niessen CM, Offermanns S, Wickström SA, Worzfeld T. Jiang C, et al. Among authors: oleksy a. Nat Commun. 2021 Feb 26;12(1):1308. doi: 10.1038/s41467-021-21513-9. Nat Commun. 2021. PMID: 33637728 Free PMC article.
A semaphorin-plexin-Rasal1 signaling pathway inhibits gastrin expression and protects against peptic ulcers.
Xu R, Höß C, Swiercz JM, Brandt DT, Lutz V, Petersen N, Li R, Zhao D, Oleksy A, Creigh-Pulatmen T, Trokter M, Fedorova M, Atzberger A, Strandby RB, Olsen AA, Achiam MP, Matthews D, Huber M, Gröne HJ, Offermanns S, Worzfeld T. Xu R, et al. Among authors: oleksy a. Sci Transl Med. 2022 Jul 20;14(654):eabf1922. doi: 10.1126/scitranslmed.abf1922. Epub 2022 Jul 20. Sci Transl Med. 2022. PMID: 35857828
An antagonistic monoclonal anti-Plexin-B1 antibody exerts therapeutic effects in mouse models of postmenopausal osteoporosis and multiple sclerosis.
Vogler M, Oleksy A, Schulze S, Fedorova M, Kojonazarov B, Nijjar S, Patel S, Jossi S, Sawmynaden K, Henry M, Brown R, Matthews D, Offermanns S, Worzfeld T. Vogler M, et al. Among authors: oleksy a. J Biol Chem. 2022 Sep;298(9):102265. doi: 10.1016/j.jbc.2022.102265. Epub 2022 Jul 15. J Biol Chem. 2022. PMID: 35850304 Free PMC article.
The molecular basis of RhoA specificity in the guanine nucleotide exchange factor PDZ-RhoGEF.
Oleksy A, Opaliński Ł, Derewenda U, Derewenda ZS, Otlewski J. Oleksy A, et al. J Biol Chem. 2006 Oct 27;281(43):32891-7. doi: 10.1074/jbc.M606220200. Epub 2006 Sep 5. J Biol Chem. 2006. PMID: 16954208 Free article.
Based on the recently solved crystal structure of the DH-PH tandem of PDZ-RhoGEF in complex with RhoA (Derewenda, U., Oleksy, A., Stevenson, A. S., Korczynska, J., Dauter, Z., Somlyo, A. ...We show that while Trp(58) of RhoA is intimately involved in t …
Based on the recently solved crystal structure of the DH-PH tandem of PDZ-RhoGEF in complex with RhoA (Derewenda, U., Oleksy, A …
Novel peptide recognized by RhoA GTPase.
Drulis-Fajdasz D, Jelen F, Oleksy A, Otlewski J. Drulis-Fajdasz D, et al. Among authors: oleksy a. Acta Biochim Pol. 2006;53(3):515-24. Epub 2006 Oct 1. Acta Biochim Pol. 2006. PMID: 17019437 Free article.
32 results