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Community-driven citizen science approach to explore cardiovascular disease risk perception, and develop prevention advocacy strategies in sub-Saharan Africa: a programme protocol.
Okop KJ, Murphy K, Lambert EV, Kedir K, Getachew H, Howe R, Niyibizi JB, Ntawuyirushintege S, Bavuma C, Rulisa S, Kasenda S, Chipeta E, Bunn C, Crampin AC, Chapotera G, King AC, Banchoff A, Winter SJ, Levitt NS. Okop KJ, et al. Among authors: howe r. Res Involv Engagem. 2021 Feb 26;7(1):11. doi: 10.1186/s40900-020-00246-x. Res Involv Engagem. 2021. PMID: 33637131 Free PMC article.
A blood RNA signature for tuberculosis disease risk: a prospective cohort study.
Zak DE, Penn-Nicholson A, Scriba TJ, Thompson E, Suliman S, Amon LM, Mahomed H, Erasmus M, Whatney W, Hussey GD, Abrahams D, Kafaar F, Hawkridge T, Verver S, Hughes EJ, Ota M, Sutherland J, Howe R, Dockrell HM, Boom WH, Thiel B, Ottenhoff THM, Mayanja-Kizza H, Crampin AC, Downing K, Hatherill M, Valvo J, Shankar S, Parida SK, Kaufmann SHE, Walzl G, Aderem A, Hanekom WA; ACS and GC6-74 cohort study groups. Zak DE, et al. Among authors: howe r. Lancet. 2016 Jun 4;387(10035):2312-2322. doi: 10.1016/S0140-6736(15)01316-1. Epub 2016 Mar 24. Lancet. 2016. PMID: 27017310 Free PMC article.
Validation and Optimization of Host Immunological Bio-Signatures for a Point-of-Care Test for TB Disease.
Mutavhatsindi H, van der Spuy GD, Malherbe ST, Sutherland JS, Geluk A, Mayanja-Kizza H, Crampin AC, Kassa D, Howe R, Mihret A, Sheehama JA, Nepolo E, Günther G, Dockrell HM, Corstjens PLAM, Stanley K, Walzl G, Chegou NN; AE-TBC ScreenTB Consortia. Mutavhatsindi H, et al. Among authors: howe r. Front Immunol. 2021 Feb 26;12:607827. doi: 10.3389/fimmu.2021.607827. eCollection 2021. Front Immunol. 2021. PMID: 33717089 Free PMC article.
Evaluation of cytokine responses against novel Mtb antigens as diagnostic markers for TB disease.
Awoniyi DO, Teuchert A, Sutherland JS, Mayanja-Kizza H, Howe R, Mihret A, Loxton AG, Sheehama J, Kassa D, Crampin AC, Dockrell HM, Kidd M, Rosenkrands I, Geluk A, Ottenhoff TH, Corstjens PL, Chegou NN, Walzl G; AE-TBC Consortium. Awoniyi DO, et al. Among authors: howe r. J Infect. 2016 Sep;73(3):219-30. doi: 10.1016/j.jinf.2016.04.036. Epub 2016 Jun 14. J Infect. 2016. PMID: 27311746 Free article.
Africa-wide evaluation of host biomarkers in QuantiFERON supernatants for the diagnosis of pulmonary tuberculosis.
Chegou NN, Sutherland JS, Namuganga AR, Corstjens PL, Geluk A, Gebremichael G, Mendy J, Malherbe S, Stanley K, van der Spuy GD, Kriel M, Loxton AG, Kriel B, Simukonda F, Bekele Y, Sheehama JA, Nelongo J, van der Vyver M, Gebrexabher A, Hailu H, Esterhuyse MM, Rosenkrands I, Aagard C, Kidd M, Kassa D, Mihret A, Howe R, Cliff JM, Crampin AC, Mayanja-Kizza H, Kaufmann SHE, Dockrell HM, Ottenhoff THM, Walzl G; AE-TBC consortium. Chegou NN, et al. Among authors: howe r. Sci Rep. 2018 Feb 8;8(1):2675. doi: 10.1038/s41598-018-20855-7. Sci Rep. 2018. PMID: 29422548 Free PMC article.
Four-Gene Pan-African Blood Signature Predicts Progression to Tuberculosis.
Suliman S, Thompson EG, Sutherland J, Weiner J 3rd, Ota MOC, Shankar S, Penn-Nicholson A, Thiel B, Erasmus M, Maertzdorf J, Duffy FJ, Hill PC, Hughes EJ, Stanley K, Downing K, Fisher ML, Valvo J, Parida SK, van der Spuy G, Tromp G, Adetifa IMO, Donkor S, Howe R, Mayanja-Kizza H, Boom WH, Dockrell HM, Ottenhoff THM, Hatherill M, Aderem A, Hanekom WA, Scriba TJ, Kaufmann SHE, Zak DE, Walzl G; GC6-74 cohort study team, The ACS cohort study team. Suliman S, et al. Among authors: howe r. Am J Respir Crit Care Med. 2018 May 1;197(9):1198-1208. doi: 10.1164/rccm.201711-2340OC. Am J Respir Crit Care Med. 2018. PMID: 29624071 Free PMC article.
Diagnostic performance of a seven-marker serum protein biosignature for the diagnosis of active TB disease in African primary healthcare clinic attendees with signs and symptoms suggestive of TB.
Chegou NN, Sutherland JS, Malherbe S, Crampin AC, Corstjens PL, Geluk A, Mayanja-Kizza H, Loxton AG, van der Spuy G, Stanley K, Kotzé LA, van der Vyver M, Rosenkrands I, Kidd M, van Helden PD, Dockrell HM, Ottenhoff TH, Kaufmann SH, Walzl G; AE-TBC consortium. Chegou NN, et al. Thorax. 2016 Sep;71(9):785-94. doi: 10.1136/thoraxjnl-2015-207999. Epub 2016 May 4. Thorax. 2016. PMID: 27146200 Free article.
RISK6, a 6-gene transcriptomic signature of TB disease risk, diagnosis and treatment response.
Penn-Nicholson A, Mbandi SK, Thompson E, Mendelsohn SC, Suliman S, Chegou NN, Malherbe ST, Darboe F, Erasmus M, Hanekom WA, Bilek N, Fisher M, Kaufmann SHE, Winter J, Murphy M, Wood R, Morrow C, Van Rhijn I, Moody B, Murray M, Andrade BB, Sterling TR, Sutherland J, Naidoo K, Padayatchi N, Walzl G, Hatherill M, Zak D, Scriba TJ; Adolescent Cohort Study team; GC6-74 Consortium; SATVI Clinical and Laboratory Team; ScreenTB Consortium; AE-TBC Consortium; RePORT Brazil Team; Peruvian Household Contacts Cohort Team; CAPRISA IMPRESS team. Penn-Nicholson A, et al. Sci Rep. 2020 May 25;10(1):8629. doi: 10.1038/s41598-020-65043-8. Sci Rep. 2020. PMID: 32451443 Free PMC article.
Multi-center evaluation of a user-friendly lateral flow assay to determine IP-10 and CCL4 levels in blood of TB and non-TB cases in Africa.
Corstjens PL, Tjon Kon Fat EM, de Dood CJ, van der Ploeg-van Schip JJ, Franken KL, Chegou NN, Sutherland JS, Howe R, Mihret A, Kassa D, van der Vyver M, Sheehama J, Simukonda F, Mayanja-Kizza H, Ottenhoff TH, Walzl G, Geluk A; AE-TBC consortium. Corstjens PL, et al. Among authors: howe r. Clin Biochem. 2016 Jan;49(1-2):22-31. doi: 10.1016/j.clinbiochem.2015.08.013. Epub 2015 Aug 15. Clin Biochem. 2016. PMID: 26285074
796 results