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Page 1
Targeting malaria protein kinases.
Cassiano GC, Tavella TA, Nascimento MN, Rodrigues DA, Cravo PVL, Andrade CH, Costa FTM. Cassiano GC, et al. Among authors: tavella ta. Adv Protein Chem Struct Biol. 2021;124:225-274. doi: 10.1016/bs.apcsb.2020.10.004. Epub 2020 Nov 1. Adv Protein Chem Struct Biol. 2021. PMID: 33632466 Review.
Hydroxyazole scaffold-based Plasmodium falciparum dihydroorotate dehydrogenase inhibitors: Synthesis, biological evaluation and X-ray structural studies.
Pippione AC, Sainas S, Goyal P, Fritzson I, Cassiano GC, Giraudo A, Giorgis M, Tavella TA, Bagnati R, Rolando B, Caing-Carlsson R, Costa FTM, Andrade CH, Al-Karadaghi S, Boschi D, Friemann R, Lolli ML. Pippione AC, et al. Among authors: tavella ta. Eur J Med Chem. 2019 Feb 1;163:266-280. doi: 10.1016/j.ejmech.2018.11.044. Epub 2018 Nov 22. Eur J Med Chem. 2019. PMID: 30529545 Free article.
Computational Chemogenomics Drug Repositioning Strategy Enables the Discovery of Epirubicin as a New Repurposed Hit for Plasmodium falciparum and P. vivax.
Ferreira LT, Rodrigues J, Cassiano GC, Tavella TA, Tomaz KCP, Baia-da-Silva DC, Souza MF, Lima MNDN, Mottin M, Almeida LD, Calit J, Puça MCSB, Melo GC, Bargieri DY, Lopes SCP, Lacerda MVG, Bilsland E, Sunnerhagen P, Neves BJ, Andrade CH, Cravo PVL, Costa FTM. Ferreira LT, et al. Among authors: tavella ta. Antimicrob Agents Chemother. 2020 Aug 20;64(9):e02041-19. doi: 10.1128/AAC.02041-19. Print 2020 Aug 20. Antimicrob Agents Chemother. 2020. PMID: 32601162 Free PMC article.
Methylprednisolone as Adjunctive Therapy for Patients Hospitalized With Coronavirus Disease 2019 (COVID-19; Metcovid): A Randomized, Double-blind, Phase IIb, Placebo-controlled Trial.
Jeronimo CMP, Farias MEL, Val FFA, Sampaio VS, Alexandre MAA, Melo GC, Safe IP, Borba MGS, Netto RLA, Maciel ABS, Neto JRS, Oliveira LB, Figueiredo EFG, Oliveira Dinelly KM, de Almeida Rodrigues MG, Brito M, Mourão MPG, Pivoto João GA, Hajjar LA, Bassat Q, Romero GAS, Naveca FG, Vasconcelos HL, de Araújo Tavares M, Brito-Sousa JD, Costa FTM, Nogueira ML, Baía-da-Silva DC, Xavier MS, Monteiro WM, Lacerda MVG; Metcovid Team. Jeronimo CMP, et al. Clin Infect Dis. 2021 May 4;72(9):e373-e381. doi: 10.1093/cid/ciaa1177. Clin Infect Dis. 2021. PMID: 32785710 Free PMC article. Clinical Trial.
Correction for Ferreira et al., "Computational Chemogenomics Drug Repositioning Strategy Enables the Discovery of Epirubicin as a New Repurposed Hit for Plasmodium falciparum and P. vivax".
Ferreira LT, Rodrigues J, Cassiano GC, Tavella TA, Tomaz KCP, Baia-da-Silva DC, Souza MF, Lima MNDN, Mottin M, Almeida LD, Calit J, Puça MCSB, Melo GC, Bargieri DY, Lopes SCP, Lacerda MVG, Bilsland E, Sunnerhagen P, Neves BJ, Andrade CH, Cravo PVL, Costa FTM. Ferreira LT, et al. Among authors: tavella ta. Antimicrob Agents Chemother. 2020 Oct 20;64(11):e01843-20. doi: 10.1128/AAC.01843-20. Print 2020 Oct 20. Antimicrob Agents Chemother. 2020. PMID: 33082230 Free PMC article. No abstract available.
Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine and Pyronaridine: In vitro Activity Against SARS-CoV-2 and Potential Mechanisms.
Puhl AC, Fritch EJ, Lane TR, Tse LV, Yount BL, Sacramento CQ, Tavella TA, Costa FTM, Weston S, Logue J, Frieman M, Premkumar L, Pearce KH, Hurst BL, Andrade CH, Levi JA, Johnson NJ, Kisthardt SC, Scholle F, Souza TML, Moorman NJ, Baric RS, Madrid P, Ekins S. Puhl AC, et al. Among authors: tavella ta. bioRxiv [Preprint]. 2020 Dec 2:2020.12.01.407361. doi: 10.1101/2020.12.01.407361. bioRxiv. 2020. PMID: 33299990 Free PMC article. Updated. Preprint.
Violacein-Induced Chaperone System Collapse Underlies Multistage Antiplasmodial Activity.
Tavella TA, da Silva NSM, Spillman N, Kayano ACAV, Cassiano GC, Vasconcelos AA, Camargo AP, da Silva DCB, Fontinha D, Salazar Alvarez LC, Ferreira LT, Peralis Tomaz KC, Neves BJ, Almeida LD, Bargieri DY, Lacerda MVG, Lemos Cravo PV, Sunnerhagen P, Prudêncio M, Andrade CH, Pinto Lopes SC, Carazzolle MF, Tilley L, Bilsland E, Borges JC, Maranhão-Costa FTM. Tavella TA, et al. ACS Infect Dis. 2021 Apr 9;7(4):759-776. doi: 10.1021/acsinfecdis.0c00454. Epub 2021 Mar 10. ACS Infect Dis. 2021. PMID: 33689276 Free PMC article.
20 results