Druley T - Search Results

1

A Non-stop identity complex (NIC) supervises enterocyte identity and protects from premature aging.

Erez N, Israitel L, Bitman-Lotan E, Wong WH, Raz G, Cornelio-Parra DV, Danial S, Flint Brodsly N, Belova E, Maksimenko O, Georgiev P, Druley T, Mohan RD, Orian A. Erez N, et al. Among authors: druley t. Elife. 2021 Feb 25;10:e62312. doi: 10.7554/eLife.62312. Elife. 2021. PMID: 33629655 Free PMC article.

2

Rare Event Detection Using Error-corrected DNA and RNA Sequencing.

Wong WH, Tong RS, Young AL, Druley TE. Wong WH, et al. J Vis Exp. 2018 Aug 3;(138):57509. doi: 10.3791/57509. J Vis Exp. 2018. PMID: 30124656 Free PMC article.

3

NF1 glioblastoma clonal profiling reveals KMT2B mutations as potential somatic oncogenic events.

Wong WH, Junck L, Druley TE, Gutmann DH. Wong WH, et al. Neurology. 2019 Dec 10;93(24):1067-1069. doi: 10.1212/WNL.0000000000008623. Epub 2019 Nov 5. Neurology. 2019. PMID: 31690684 No abstract available.

4

Loss of KMT2C reprograms the epigenomic landscape in hPSCs resulting in NODAL overexpression and a failure of hemogenic endothelium specification.

Maurya S, Yang W, Tamai M, Zhang Q, Erdmann-Gilmore P, Bystry A, Martins Rodrigues F, Valentine MC, Wong WH, Townsend R, Druley TE. Maurya S, et al. Among authors: druley te. Epigenetics. 2022 Jan-Feb;17(2):220-238. doi: 10.1080/15592294.2021.1954780. Epub 2021 Jul 24. Epigenetics. 2022. PMID: 34304711 Free PMC article.

5

The evolutionary dynamics and fitness landscape of clonal hematopoiesis.

Watson CJ, Papula AL, Poon GYP, Wong WH, Young AL, Druley TE, Fisher DS, Blundell JR. Watson CJ, et al. Science. 2020 Mar 27;367(6485):1449-1454. doi: 10.1126/science.aay9333. Science. 2020. PMID: 32217721

6

Error-corrected sequencing strategies enable comprehensive detection of leukemic mutations relevant for diagnosis and minimal residual disease monitoring.

Crowgey EL, Mahajan N, Wong WH, Gopalakrishnapillai A, Barwe SP, Kolb EA, Druley TE. Crowgey EL, et al. BMC Med Genomics. 2020 Mar 4;13(1):32. doi: 10.1186/s12920-020-0671-8. BMC Med Genomics. 2020. PMID: 32131829 Free PMC article.

7

Engraftment of rare, pathogenic donor hematopoietic mutations in unrelated hematopoietic stem cell transplantation.

Wong WH, Bhatt S, Trinkaus K, Pusic I, Elliott K, Mahajan N, Wan F, Switzer GE, Confer DL, DiPersio J, Pulsipher MA, Shah NN, Sees J, Bystry A, Blundell JR, Shaw BE, Druley TE. Wong WH, et al. Sci Transl Med. 2020 Jan 15;12(526):eaax6249. doi: 10.1126/scitranslmed.aax6249. Sci Transl Med. 2020. PMID: 31941826 Free PMC article.

8

Age-specific changes in genome-wide methylation enrich for Foxa2 and estrogen receptor alpha binding sites.

Uli N, Michelen-Gomez E, Ramos EI, Druley TE. Uli N, et al. PLoS One. 2018 Sep 26;13(9):e0203147. doi: 10.1371/journal.pone.0203147. eCollection 2018. PLoS One. 2018. PMID: 30256791 Free PMC article.

9

Clonal hematopoiesis and risk of acute myeloid leukemia.

Young AL, Tong RS, Birmann BM, Druley TE. Young AL, et al. Haematologica. 2019 Dec;104(12):2410-2417. doi: 10.3324/haematol.2018.215269. Epub 2019 Apr 19. Haematologica. 2019. PMID: 31004019 Free PMC article.

10

Clonal haematopoiesis harbouring AML-associated mutations is ubiquitous in healthy adults.

Young AL, Challen GA, Birmann BM, Druley TE. Young AL, et al. Nat Commun. 2016 Aug 22;7:12484. doi: 10.1038/ncomms12484. Nat Commun. 2016. PMID: 27546487 Free PMC article.

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