Leung AYH - Search Results

1

Functional reconstruction of human AML reveals stem cell origin and vulnerability of treatment-resistant MLL-rearranged leukemia.

Zeisig BB, Fung TK, Zarowiecki M, Tsai CT, Luo H, Stanojevic B, Lynn C, Leung AYH, Zuna J, Zaliova M, Bornhauser M, von Bonin M, Lenhard B, Huang S, Mufti GJ, So CWE. Zeisig BB, et al. Among authors: leung ayh. Sci Transl Med. 2021 Feb 24;13(582):eabc4822. doi: 10.1126/scitranslmed.abc4822. Sci Transl Med. 2021. PMID: 33627486

2

Aldehyde dehydrogenase activity in leukemic blasts defines a subgroup of acute myeloid leukemia with adverse prognosis and superior NOD/SCID engrafting potential.

Cheung AM, Wan TS, Leung JC, Chan LY, Huang H, Kwong YL, Liang R, Leung AY. Cheung AM, et al. Leukemia. 2007 Jul;21(7):1423-30. doi: 10.1038/sj.leu.2404721. Epub 2007 May 3. Leukemia. 2007. PMID: 17476279

3

Methionine aminopeptidase 2 is required for HSC initiation and proliferation.

Ma AC, Fung TK, Lin RH, Chung MI, Yang D, Ekker SC, Leung AY. Ma AC, et al. Blood. 2011 Nov 17;118(20):5448-57. doi: 10.1182/blood-2011-04-350173. Epub 2011 Sep 21. Blood. 2011. PMID: 21937698 Free PMC article.

4

Sorafenib treatment of FLT3-ITD(+) acute myeloid leukemia: favorable initial outcome and mechanisms of subsequent nonresponsiveness associated with the emergence of a D835 mutation.

Man CH, Fung TK, Ho C, Han HH, Chow HC, Ma AC, Choi WW, Lok S, Cheung AM, Eaves C, Kwong YL, Leung AY. Man CH, et al. Blood. 2012 May 31;119(22):5133-43. doi: 10.1182/blood-2011-06-363960. Epub 2012 Feb 24. Blood. 2012. PMID: 22368270 Free article. Clinical Trial.

5

Functions of flt3 in zebrafish hematopoiesis and its relevance to human acute myeloid leukemia.

He BL, Shi X, Man CH, Ma AC, Ekker SC, Chow HC, So CW, Choi WW, Zhang W, Zhang Y, Leung AY. He BL, et al. Blood. 2014 Apr 17;123(16):2518-29. doi: 10.1182/blood-2013-02-486688. Epub 2014 Mar 3. Blood. 2014. PMID: 24591202 Free PMC article.

6

Suppression of SOX7 by DNA methylation and its tumor suppressor function in acute myeloid leukemia.

Man CH, Fung TK, Wan H, Cher CY, Fan A, Ng N, Ho C, Wan TS, Tanaka T, So CW, Kwong YL, Leung AY. Man CH, et al. Blood. 2015 Jun 18;125(25):3928-36. doi: 10.1182/blood-2014-06-580993. Epub 2015 May 4. Blood. 2015. PMID: 25940713 Free article.

7

Homoharringtonine (omacetaxine mepesuccinate) as an adjunct for FLT3-ITD acute myeloid leukemia.

Lam SS, Ho ES, He BL, Wong WW, Cher CY, Ng NK, Man CH, Gill H, Cheung AM, Ip HW, So CC, Tamburini J, So CW, Ho DN, Au CH, Chan TL, Ma ES, Liang R, Kwong YL, Leung AY. Lam SS, et al. Sci Transl Med. 2016 Oct 5;8(359):359ra129. doi: 10.1126/scitranslmed.aaf3735. Sci Transl Med. 2016. PMID: 27708062 Clinical Trial.

8

Overcoming Resistance to FLT3 Inhibitors in the Treatment of FLT3-Mutated AML.

Lam SSY, Leung AYH. Lam SSY, et al. Among authors: leung ayh. Int J Mol Sci. 2020 Feb 24;21(4):1537. doi: 10.3390/ijms21041537. Int J Mol Sci. 2020. PMID: 32102366 Free PMC article. Review.

9

A comparative study of bone marrow and peripheral blood CD34+ myeloblasts in acute myeloid leukaemia.

Cheung AM, Chow HC, Liang R, Leung AY. Cheung AM, et al. Br J Haematol. 2009 Feb;144(4):484-91. doi: 10.1111/j.1365-2141.2008.07431.x. Epub 2008 Dec 1. Br J Haematol. 2009. PMID: 19055666 Free article.

10

FLT3/internal tandem duplication subclones in acute myeloid leukemia differ in their engraftment potential in NOD/SCID mice.

Cheung AM, Chow HC, Kwong YL, Liang R, Leung AY. Cheung AM, et al. Leuk Res. 2010 Jan;34(1):119-22. doi: 10.1016/j.leukres.2009.07.035. Epub 2009 Aug 15. Leuk Res. 2010. PMID: 19683812

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