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Functional reconstruction of human AML reveals stem cell origin and vulnerability of treatment-resistant MLL-rearranged leukemia.
Zeisig BB, Fung TK, Zarowiecki M, Tsai CT, Luo H, Stanojevic B, Lynn C, Leung AYH, Zuna J, Zaliova M, Bornhauser M, von Bonin M, Lenhard B, Huang S, Mufti GJ, So CWE. Zeisig BB, et al. Among authors: lenhard b. Sci Transl Med. 2021 Feb 24;13(582):eabc4822. doi: 10.1126/scitranslmed.abc4822. Sci Transl Med. 2021. PMID: 33627486
Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation.
Cuartero S, Weiss FD, Dharmalingam G, Guo Y, Ing-Simmons E, Masella S, Robles-Rebollo I, Xiao X, Wang YF, Barozzi I, Djeghloul D, Amano MT, Niskanen H, Petretto E, Dowell RD, Tachibana K, Kaikkonen MU, Nasmyth KA, Lenhard B, Natoli G, Fisher AG, Merkenschlager M. Cuartero S, et al. Among authors: lenhard b. Nat Immunol. 2018 Sep;19(9):932-941. doi: 10.1038/s41590-018-0184-1. Epub 2018 Aug 20. Nat Immunol. 2018. PMID: 30127433 Free PMC article.
Promoter architectures and developmental gene regulation.
Haberle V, Lenhard B. Haberle V, et al. Among authors: lenhard b. Semin Cell Dev Biol. 2016 Sep;57:11-23. doi: 10.1016/j.semcdb.2016.01.014. Epub 2016 Jan 16. Semin Cell Dev Biol. 2016. PMID: 26783721 Free article. Review.
Core promoters across the genome.
Cvetesic N, Lenhard B. Cvetesic N, et al. Among authors: lenhard b. Nat Biotechnol. 2017 Feb 8;35(2):123-124. doi: 10.1038/nbt.3788. Nat Biotechnol. 2017. PMID: 28178253 Free article. No abstract available.
187 results