Fung TK - Search Results

1

Functional reconstruction of human AML reveals stem cell origin and vulnerability of treatment-resistant MLL-rearranged leukemia.

Zeisig BB, Fung TK, Zarowiecki M, Tsai CT, Luo H, Stanojevic B, Lynn C, Leung AYH, Zuna J, Zaliova M, Bornhauser M, von Bonin M, Lenhard B, Huang S, Mufti GJ, So CWE. Zeisig BB, et al. Among authors: fung tk. Sci Transl Med. 2021 Feb 24;13(582):eabc4822. doi: 10.1126/scitranslmed.abc4822. Sci Transl Med. 2021. PMID: 33627486

2

Transcriptional memory of cells of origin overrides β-catenin requirement of MLL cancer stem cells.

Siriboonpiputtana T, Zeisig BB, Zarowiecki M, Fung TK, Mallardo M, Tsai CT, Lau PNI, Hoang QC, Veiga P, Barnes J, Lynn C, Wilson A, Lenhard B, So CWE. Siriboonpiputtana T, et al. Among authors: fung tk. EMBO J. 2017 Nov 2;36(21):3139-3155. doi: 10.15252/embj.201797994. Epub 2017 Oct 4. EMBO J. 2017. PMID: 28978671 Free PMC article.

3

HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice.

Luo H, Zhu G, Xu J, Lai Q, Yan B, Guo Y, Fung TK, Zeisig BB, Cui Y, Zha J, Cogle C, Wang F, Xu B, Yang FC, Li W, So CWE, Qiu Y, Xu M, Huang S. Luo H, et al. Among authors: fung tk. Cancer Cell. 2019 Dec 9;36(6):645-659.e8. doi: 10.1016/j.ccell.2019.10.011. Epub 2019 Nov 27. Cancer Cell. 2019. PMID: 31786140 Free PMC article.

4

Sox4you: a new player in C/EBPα leukemia.

Fung TK, Leung AY, So CW. Fung TK, et al. Cancer Cell. 2013 Nov 11;24(5):557-9. doi: 10.1016/j.ccr.2013.10.016. Cancer Cell. 2013. PMID: 24229703 Free article.

5

Synthetic lethal targeting of oncogenic transcription factors in acute leukemia by PARP inhibitors.

Esposito MT, Zhao L, Fung TK, Rane JK, Wilson A, Martin N, Gil J, Leung AY, Ashworth A, So CW. Esposito MT, et al. Among authors: fung tk. Nat Med. 2015 Dec;21(12):1481-90. doi: 10.1038/nm.3993. Epub 2015 Nov 23. Nat Med. 2015. PMID: 26594843

6

Targeting Aberrant Epigenetic Networks Mediated by PRMT1 and KDM4C in Acute Myeloid Leukemia.

Cheung N, Fung TK, Zeisig BB, Holmes K, Rane JK, Mowen KA, Finn MG, Lenhard B, Chan LC, So CW. Cheung N, et al. Among authors: fung tk. Cancer Cell. 2016 Jan 11;29(1):32-48. doi: 10.1016/j.ccell.2015.12.007. Cancer Cell. 2016. PMID: 26766589 Free PMC article.

7

Reconstruction of Human AML Using Functionally and Immunophenotypically Defined Human Haematopoietic Stem and Progenitor Cells as Targeted Populations.

Zeisig BB, Fung TK, Troadec E, So CWE. Zeisig BB, et al. Among authors: fung tk. Bio Protoc. 2021 Dec 20;11(24):e4262. doi: 10.21769/BioProtoc.4262. eCollection 2021 Dec 20. Bio Protoc. 2021. PMID: 35087921 Free PMC article.

8

HOTTIP-dependent R-loop formation regulates CTCF boundary activity and TAD integrity in leukemia.

Luo H, Zhu G, Eshelman MA, Fung TK, Lai Q, Wang F, Zeisig BB, Lesperance J, Ma X, Chen S, Cesari N, Cogle C, Chen B, Xu B, Yang FC, So CWE, Qiu Y, Xu M, Huang S. Luo H, et al. Among authors: fung tk. Mol Cell. 2022 Feb 17;82(4):833-851.e11. doi: 10.1016/j.molcel.2022.01.014. Mol Cell. 2022. PMID: 35180428 Free PMC article.

9

Suppression of SOX7 by DNA methylation and its tumor suppressor function in acute myeloid leukemia.

Man CH, Fung TK, Wan H, Cher CY, Fan A, Ng N, Ho C, Wan TS, Tanaka T, So CW, Kwong YL, Leung AY. Man CH, et al. Among authors: fung tk. Blood. 2015 Jun 18;125(25):3928-36. doi: 10.1182/blood-2014-06-580993. Epub 2015 May 4. Blood. 2015. PMID: 25940713 Free article.

10

Sorafenib treatment of FLT3-ITD(+) acute myeloid leukemia: favorable initial outcome and mechanisms of subsequent nonresponsiveness associated with the emergence of a D835 mutation.

Man CH, Fung TK, Ho C, Han HH, Chow HC, Ma AC, Choi WW, Lok S, Cheung AM, Eaves C, Kwong YL, Leung AY. Man CH, et al. Among authors: fung tk. Blood. 2012 May 31;119(22):5133-43. doi: 10.1182/blood-2011-06-363960. Epub 2012 Feb 24. Blood. 2012. PMID: 22368270 Free article. Clinical Trial.

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