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Gestational long-term hypoxia induces metabolomic reprogramming and phenotypic transformations in fetal sheep pulmonary arteries.
Leslie E, Lopez V, Anti NAO, Alvarez R, Kafeero I, Welsh DG, Romero M, Kaushal S, Johnson CM, Bosviel R, Blaženović I, Song R, Brito A, Frano MR, Zhang L, Newman JW, Fiehn O, Wilson SM. Leslie E, et al. Among authors: fiehn o. Am J Physiol Lung Cell Mol Physiol. 2021 May 1;320(5):L770-L784. doi: 10.1152/ajplung.00469.2020. Epub 2021 Feb 24. Am J Physiol Lung Cell Mol Physiol. 2021. PMID: 33624555 Free PMC article.
Improved metabolic health alters host metabolism in parallel with changes in systemic xeno-metabolites of gut origin.
Campbell C, Grapov D, Fiehn O, Chandler CJ, Burnett DJ, Souza EC, Casazza GA, Gustafson MB, Keim NL, Newman JW, Hunter GR, Fernandez JR, Garvey WT, Harper ME, Hoppel CL, Meissen JK, Take K, Adams SH. Campbell C, et al. Among authors: fiehn o. PLoS One. 2014 Jan 8;9(1):e84260. doi: 10.1371/journal.pone.0084260. eCollection 2014. PLoS One. 2014. PMID: 24416208 Free PMC article. Clinical Trial.
High-dose simvastatin exhibits enhanced lipid-lowering effects relative to simvastatin/ezetimibe combination therapy.
Snowden SG, Grapov D, Settergren M, D'Alexandri FL, Haeggström JZ, Fiehn O, Hyötyläinen T, Pedersen TL, Newman JW, Orešič M, Pernow J, Wheelock CE. Snowden SG, et al. Among authors: fiehn o. Circ Cardiovasc Genet. 2014 Dec;7(6):955-964. doi: 10.1161/CIRCGENETICS.114.000606. Circ Cardiovasc Genet. 2014. PMID: 25516625 Free PMC article. Clinical Trial.
Acylcarnitines as markers of exercise-associated fuel partitioning, xenometabolism, and potential signals to muscle afferent neurons.
Zhang J, Light AR, Hoppel CL, Campbell C, Chandler CJ, Burnett DJ, Souza EC, Casazza GA, Hughen RW, Keim NL, Newman JW, Hunter GR, Fernandez JR, Garvey WT, Harper ME, Fiehn O, Adams SH. Zhang J, et al. Among authors: fiehn o. Exp Physiol. 2017 Jan 1;102(1):48-69. doi: 10.1113/EP086019. Epub 2016 Dec 12. Exp Physiol. 2017. PMID: 27730694 Free PMC article.
Umbilical cord blood metabolomics reveal distinct signatures of dyslipidemia prior to bronchopulmonary dysplasia and pulmonary hypertension.
La Frano MR, Fahrmann JF, Grapov D, Pedersen TL, Newman JW, Fiehn O, Underwood MA, Mestan K, Steinhorn RH, Wedgwood S. La Frano MR, et al. Among authors: fiehn o. Am J Physiol Lung Cell Mol Physiol. 2018 Nov 1;315(5):L870-L881. doi: 10.1152/ajplung.00283.2017. Epub 2018 Aug 16. Am J Physiol Lung Cell Mol Physiol. 2018. PMID: 30113229 Free PMC article.
493 results