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Stable tumor vessel normalization with pO₂ increase and endothelial PTEN activation by inositol trispyrophosphate brings novel tumor treatment.
Kieda C, El Hafny-Rahbi B, Collet G, Lamerant-Fayel N, Grillon C, Guichard A, Dulak J, Jozkowicz A, Kotlinowski J, Fylaktakidou KC, Vidal A, Auzeloux P, Miot-Noirault E, Beloeil JC, Lehn JM, Nicolau C. Kieda C, et al. Among authors: el hafny rahbi b. J Mol Med (Berl). 2013 Jul;91(7):883-99. doi: 10.1007/s00109-013-0992-6. Epub 2013 Mar 9. J Mol Med (Berl). 2013. PMID: 23471434 Free PMC article.
Hypoxia-regulated overexpression of soluble VEGFR2 controls angiogenesis and inhibits tumor growth.
Collet G, Lamerant-Fayel N, Tertil M, El Hafny-Rahbi B, Stepniewski J, Guichard A, Foucault-Collet A, Klimkiewicz K, Petoud S, Matejuk A, Grillon C, Jozkowicz A, Dulak J, Kieda C. Collet G, et al. Among authors: el hafny rahbi b. Mol Cancer Ther. 2014 Jan;13(1):165-78. doi: 10.1158/1535-7163.MCT-13-0637. Epub 2013 Oct 29. Mol Cancer Ther. 2014. PMID: 24170768 Free PMC article.
Hypoxia-shaped vascular niche for cancer stem cells.
Collet G, El Hafny-Rahbi B, Nadim M, Tejchman A, Klimkiewicz K, Kieda C. Collet G, et al. Among authors: el hafny rahbi b. Contemp Oncol (Pozn). 2015;19(1A):A39-43. doi: 10.5114/wo.2014.47130. Contemp Oncol (Pozn). 2015. PMID: 25691820 Free PMC article. Review.
Endothelial precursor cell-based therapy to target the pathologic angiogenesis and compensate tumor hypoxia.
Collet G, Szade K, Nowak W, Klimkiewicz K, El Hafny-Rahbi B, Szczepanek K, Sugiyama D, Weglarczyk K, Foucault-Collet A, Guichard A, Mazan A, Nadim M, Fasani F, Lamerant-Fayel N, Grillon C, Petoud S, Beloeil JC, Jozkowicz A, Dulak J, Kieda C. Collet G, et al. Among authors: el hafny rahbi b. Cancer Lett. 2016 Jan 28;370(2):345-57. doi: 10.1016/j.canlet.2015.11.008. Epub 2015 Nov 11. Cancer Lett. 2016. PMID: 26577811 Free article.