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A group of cationic amphiphilic drugs activates MRGPRX2 and induces scratching behavior in mice.
J Allergy Clin Immunol. 2021 Aug;148(2):506-522.e8. doi: 10.1016/j.jaci.2020.12.655. Epub 2021 Feb 20.
J Allergy Clin Immunol. 2021.
PMID: 33617860
MAS-related G protein-coupled receptors X (MRGPRX): Orphan GPCRs with potential as targets for future drugs.
Al Hamwi G, Riedel YK, Clemens S, Namasivayam V, Thimm D, Müller CE.
Al Hamwi G, et al. Among authors: riedel yk.
Pharmacol Ther. 2022 Oct;238:108259. doi: 10.1016/j.pharmthera.2022.108259. Epub 2022 Aug 5.
Pharmacol Ther. 2022.
PMID: 35934214
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