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A group of cationic amphiphilic drugs activates MRGPRX2 and induces scratching behavior in mice.
Wolf K, Kühn H, Boehm F, Gebhardt L, Glaudo M, Agelopoulos K, Ständer S, Ectors P, Zahn D, Riedel YK, Thimm D, Müller CE, Kretschmann S, Kremer AN, Chien D, Limjunyawong N, Peng Q, Dong X, Kolkhir P, Scheffel J, Søgaard ML, Weigmann B, Neurath MF, Hawro T, Metz M, Fischer MJM, Kremer AE. Wolf K, et al. Among authors: chien d. J Allergy Clin Immunol. 2021 Aug;148(2):506-522.e8. doi: 10.1016/j.jaci.2020.12.655. Epub 2021 Feb 20. J Allergy Clin Immunol. 2021. PMID: 33617860
Secondary (iso)BAs cooperate with endogenous ligands to activate FXR under physiological and pathological conditions.
Zaufel A, van de Wiel SMW, Yin L, Fauler G, Chien D, Dong X, Gilmer JF, Truong JK, Dawson PA, van de Graaf SFJ, Fickert P, Moustafa T. Zaufel A, et al. Among authors: chien d. Biochim Biophys Acta Mol Basis Dis. 2021 Aug 1;1867(8):166153. doi: 10.1016/j.bbadis.2021.166153. Epub 2021 Apr 22. Biochim Biophys Acta Mol Basis Dis. 2021. PMID: 33895309 Free PMC article.
High myopia at high altitudes.
Wang TW, Huang MK, Hsu CC, Jo SY, Lin YK, How CK, Tseng SF, Chung K, Chien DK, Chang WH, Chiu YH. Wang TW, et al. Among authors: chien dk. Front Physiol. 2024 Mar 8;15:1350051. doi: 10.3389/fphys.2024.1350051. eCollection 2024. Front Physiol. 2024. PMID: 38523807 Free PMC article.
231 results