MacFarlane M - Search Results

1

Patient-Derived Tumor Explants As a "Live" Preclinical Platform for Predicting Drug Resistance in Patients.

Viticchié G, Powley I, Demetriou C, Cooper J, Butterworth M, Patel M, Abid N, Miles G, Howells L, Pringle H, MacFarlane M, Pritchard C. Viticchié G, et al. Among authors: macfarlane m. J Vis Exp. 2021 Feb 7;(168). doi: 10.3791/62130. J Vis Exp. 2021. PMID: 33616105

2

Bcl-2 and Bcl-xL inhibit CD95-mediated apoptosis by preventing mitochondrial release of Smac/DIABLO and subsequent inactivation of X-linked inhibitor-of-apoptosis protein.

Sun XM, Bratton SB, Butterworth M, MacFarlane M, Cohen GM. Sun XM, et al. Among authors: macfarlane m. J Biol Chem. 2002 Mar 29;277(13):11345-51. doi: 10.1074/jbc.M109893200. Epub 2002 Jan 18. J Biol Chem. 2002. PMID: 11801595 Free article.

3

Caspase activation inhibits proteasome function during apoptosis.

Sun XM, Butterworth M, MacFarlane M, Dubiel W, Ciechanover A, Cohen GM. Sun XM, et al. Among authors: macfarlane m. Mol Cell. 2004 Apr 9;14(1):81-93. doi: 10.1016/s1097-2765(04)00156-x. Mol Cell. 2004. PMID: 15068805 Free article.

4

Reconstitution of the death-inducing signaling complex reveals a substrate switch that determines CD95-mediated death or survival.

Hughes MA, Harper N, Butterworth M, Cain K, Cohen GM, MacFarlane M. Hughes MA, et al. Among authors: macfarlane m. Mol Cell. 2009 Aug 14;35(3):265-79. doi: 10.1016/j.molcel.2009.06.012. Mol Cell. 2009. PMID: 19683492 Free article.

5

The 'complexities' of life and death: death receptor signalling platforms.

Dickens LS, Powley IR, Hughes MA, MacFarlane M. Dickens LS, et al. Among authors: macfarlane m. Exp Cell Res. 2012 Jul 1;318(11):1269-77. doi: 10.1016/j.yexcr.2012.04.005. Epub 2012 Apr 17. Exp Cell Res. 2012. PMID: 22542855 Free article. Review.

6

Modulation of the sensitivity of Jurkat T-cells to inhibition of protein synthesis by tumor necrosis factor α-related apoptosis-inducing ligand.

Elia A, Powley IR, MacFarlane M, Clemens MJ. Elia A, et al. Among authors: macfarlane m. J Interferon Cytokine Res. 2014 Oct;34(10):769-77. doi: 10.1089/jir.2013.0061. Epub 2014 Apr 14. J Interferon Cytokine Res. 2014. PMID: 24731196

7

Resistance to HSP90 inhibition involving loss of MCL1 addiction.

Busacca S, Law EW, Powley IR, Proia DA, Sequeira M, Le Quesne J, Klabatsa A, Edwards JM, Matchett KB, Luo JL, Pringle JH, El-Tanani M, MacFarlane M, Fennell DA. Busacca S, et al. Among authors: macfarlane m. Oncogene. 2016 Mar 24;35(12):1483-92. doi: 10.1038/onc.2015.213. Epub 2015 Jun 22. Oncogene. 2016. PMID: 26096930 Free PMC article.

8

Molecular profiling reveals primary mesothelioma cell lines recapitulate human disease.

Chernova T, Sun XM, Powley IR, Galavotti S, Grosso S, Murphy FA, Miles GJ, Cresswell L, Antonov AV, Bennett J, Nakas A, Dinsdale D, Cain K, Bushell M, Willis AE, MacFarlane M. Chernova T, et al. Among authors: macfarlane m. Cell Death Differ. 2016 Jul;23(7):1152-64. doi: 10.1038/cdd.2015.165. Epub 2016 Feb 19. Cell Death Differ. 2016. PMID: 26891694 Free PMC article.

9

Co-operative and Hierarchical Binding of c-FLIP and Caspase-8: A Unified Model Defines How c-FLIP Isoforms Differentially Control Cell Fate.

Hughes MA, Powley IR, Jukes-Jones R, Horn S, Feoktistova M, Fairall L, Schwabe JW, Leverkus M, Cain K, MacFarlane M. Hughes MA, et al. Among authors: macfarlane m. Mol Cell. 2016 Mar 17;61(6):834-49. doi: 10.1016/j.molcel.2016.02.023. Mol Cell. 2016. PMID: 26990987 Free PMC article.

10

Caspase-8 tyrosine-380 phosphorylation inhibits CD95 DISC function by preventing procaspase-8 maturation and cycling within the complex.

Powley IR, Hughes MA, Cain K, MacFarlane M. Powley IR, et al. Among authors: macfarlane m. Oncogene. 2016 Oct 27;35(43):5629-5640. doi: 10.1038/onc.2016.99. Epub 2016 Apr 25. Oncogene. 2016. PMID: 27109099 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

350 results

Search Page