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GSK137, a potent small-molecule BCL6 inhibitor with in vivo activity, suppresses antibody responses in mice.
Pearce AC, Bamford MJ, Barber R, Bridges A, Convery MA, Demetriou C, Evans S, Gobbetti T, Hirst DJ, Holmes DS, Hutchinson JP, Jayne S, Lezina L, McCabe MT, Messenger C, Morley J, Musso MC, Scott-Stevens P, Manso AS, Schofield J, Slocombe T, Somers D, Walker AL, Wyce A, Zhang XP, Wagner SD. Pearce AC, et al. Among authors: demetriou c. J Biol Chem. 2021 Aug;297(2):100928. doi: 10.1016/j.jbc.2021.100928. Epub 2021 Jul 15. J Biol Chem. 2021. PMID: 34274316 Free PMC article.
An optimised patient-derived explant platform for breast cancer reflects clinical responses to chemotherapy and antibody-directed therapy.
Demetriou C, Abid N, Butterworth M, Lezina L, Sandhu P, Howells L, Powley IR, Pringle JH, Sidat Z, Qassid O, Purnell D, Kaushik M, Duckworth K, Hartshorn H, Thomas A, Shaw JA, MacFarlane M, Pritchard C, Miles GJ. Demetriou C, et al. Sci Rep. 2024 Jun 4;14(1):12833. doi: 10.1038/s41598-024-63170-0. Sci Rep. 2024. PMID: 38834809 Free PMC article.
Cause-Specific Excess Mortality During the COVID-19 Pandemic (2020-2021) in 12 Countries of the C-MOR Consortium.
Beeks VV, Achilleos S, Quattrocchi A, Pallari CT, Critselis E, Salameh P, Rahmanian Haghighi MR, Rodriguez-Llanes JM, Ambrosio G, Artemiou A, Gabel J, Bennett CM, Cuthbertson J, Zimmermann C, Schernhammer ES, Costa AJL, de Carvalho LF, Lobato JCP, Athanasiadou M, Critchley JA, Goldsmith LP, Kandelaki L, Glushkova N, Davletov K, Semenova Y, Erzen I, Verstiuk O, Alekkou D, Polemitis A, Charalambous A, Demetriou CA; C-MOR Consortium. Beeks VV, et al. Among authors: demetriou ca. J Epidemiol Glob Health. 2024 May 22. doi: 10.1007/s44197-024-00242-4. Online ahead of print. J Epidemiol Glob Health. 2024. PMID: 38775902 Free article.
Magnitude and determinants of excess total, age-specific and sex-specific all-cause mortality in 24 countries worldwide during 2020 and 2021: results on the impact of the COVID-19 pandemic from the C-MOR project.
Pallari CT, Achilleos S, Quattrocchi A, Gabel J, Critselis E, Athanasiadou M, Rahmanian Haghighi MR, Papatheodorou S, Liu T, Artemiou A, Rodriguez-Llanes JM, Bennett CM, Zimmermann C, Schernhammer E, Bustos Sierra N, Ekelson R, Lobato J, Macedo L, Mortensen LH, Critchley J, Goldsmith L, Denissov G, Le Meur N, Kandelaki L, Athanasakis K, Binyaminy B, Maor T, Stracci F, Ambrosio G, Davletov K, Glushkova N, Martial C, Chan Sun M, Hagen TP, Chong M, Barron M, Łyszczarz B, Erzen I, Arcos Gonzalez P, Burström B, Pidmurniak N, Verstiuk O, Huang Q, Polemitis A, Charalambous A, Demetriou CA. Pallari CT, et al. Among authors: demetriou ca. BMJ Glob Health. 2024 Apr 18;9(4):e013018. doi: 10.1136/bmjgh-2023-013018. BMJ Glob Health. 2024. PMID: 38637119 Free PMC article.
Simvastatin in Critically Ill Patients with Covid-19.
REMAP-CAP Investigators; Hills TE, Lorenzi E, Berry LR, Shyamsundar M, Al-Beidh F, Annane D, Arabi Y, Aryal D, Au C, Beane A, Bhimani Z, Bonten M, Bradbury CA, Brunkhorst FM, Burrell A, Buxton M, Calfee CS, Cecconi M, Cheng AC, Cove ME, Detry MA, Estcourt LJ, Fitzgerald M, Goligher EC, Goossens H, Green C, Haniffa R, Harrison DA, Hashmi M, Higgins AM, Huang DT, Ichihara N, Jayakumar D, Kruger PS, Lamontagne F, Lampro L, Lawler PR, Marshall JC, Mason AJ, McGlothlin A, McGuinness S, McQuilten ZK, McVerry BJ, Mouncey PR, Murthy S, Neal MD, Nichol AD, O'Kane CM, Parke RL, Parker JC, Rabindrarajan E, Reyes LF, Rowan KM, Saito H, Santos M, Saunders CT, Seymour CW, Shankar-Hari M, Sinha P, Thompson BT, Turgeon AF, Turner AM, van de Veerdonk F, Weis S, Young IS, Zarychanski R, Lewis RJ, McArthur CJ, Angus DC, Berry SM, Derde LPG, Webb SA, Gordon AC, McAuley DF. REMAP-CAP Investigators, et al. N Engl J Med. 2023 Dec 21;389(25):2341-2354. doi: 10.1056/NEJMoa2309995. Epub 2023 Oct 25. N Engl J Med. 2023. PMID: 37888913 Free PMC article. Clinical Trial.
146 results