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Axl receptor tyrosine kinase is a regulator of apolipoprotein E.
Zhao W, Fan J, Kulic I, Koh C, Clark A, Meuller J, Engkvist O, Barichievy S, Raynoschek C, Hicks R, Maresca M, Wang Q, Brown DG, Lok A, Parro C, Robert J, Chou HY, Zuhl AM, Wood MW, Brandon NJ, Wellington CL. Zhao W, et al. Among authors: zuhl am. Mol Brain. 2020 May 4;13(1):66. doi: 10.1186/s13041-020-00609-1. Mol Brain. 2020. PMID: 32366277 Free PMC article.
Chemoproteomic profiling reveals that cathepsin D off-target activity drives ocular toxicity of β-secretase inhibitors.
Zuhl AM, Nolan CE, Brodney MA, Niessen S, Atchison K, Houle C, Karanian DA, Ambroise C, Brulet JW, Beck EM, Doran SD, O'Neill BT, Am Ende CW, Chang C, Geoghegan KF, West GM, Judkins JC, Hou X, Riddell DR, Johnson DS. Zuhl AM, et al. Nat Commun. 2016 Oct 11;7:13042. doi: 10.1038/ncomms13042. Nat Commun. 2016. PMID: 27727204 Free PMC article.
Selective inhibitor of platelet-activating factor acetylhydrolases 1b2 and 1b3 that impairs cancer cell survival.
Chang JW, Zuhl AM, Speers AE, Niessen S, Brown SJ, Mulvihill MM, Fan YC, Spicer TP, Southern M, Scampavia L, Fernandez-Vega V, Dix MM, Cameron MD, Hodder PS, Rosen H, Nomura DK, Kwon O, Hsu KL, Cravatt BF. Chang JW, et al. Among authors: zuhl am. ACS Chem Biol. 2015 Apr 17;10(4):925-32. doi: 10.1021/cb500893q. Epub 2015 Jan 20. ACS Chem Biol. 2015. PMID: 25602368 Free PMC article.
Optimization and characterization of a pan protein arginine deiminase (PAD) inhibitor.
Dreyton CJ, Jones JE, Knuckley BA, Subramanian V, Anderson ED, Brown SJ, Fernandez-Vega V, Eberhart C, Spicer T, Zuhl AM, Ferguson J, Speers AE, Wang C, Boger DL, Thompson P, Cravatt BF, Hodder P, Rosen H. Dreyton CJ, et al. Among authors: zuhl am. 2012 Dec 17 [updated 2013 Apr 5]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2012 Dec 17 [updated 2013 Apr 5]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 23833800 Free Books & Documents. Review.
Probe Development Efforts to Identify Novel Inhibitors of ABHD10.
Zuhl AM, Mohr JT, Speers AE, Bachovchin DA, Berlin JM, Spicer T, Fernandez-Vega V, Brown SJ, Ferguson J, Fu GC, Cravatt BF, Hodder P, Rosen H. Zuhl AM, et al. 2011 Dec 6 [updated 2013 Mar 7]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. 2011 Dec 6 [updated 2013 Mar 7]. In: Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010–. PMID: 23762952 Free Books & Documents. Review.
15 results