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20S proteasomes secreted by the malaria parasite promote its growth.
Dekel E, Yaffe D, Rosenhek-Goldian I, Ben-Nissan G, Ofir-Birin Y, Morandi MI, Ziv T, Sisquella X, Pimentel MA, Nebl T, Kapp E, Ohana Daniel Y, Karam PA, Alfandari D, Rotkopf R, Malihi S, Temin TB, Mullick D, Revach OY, Rudik A, Gov NS, Azuri I, Porat Z, Bergamaschi G, Sorkin R, Wuite GJL, Avinoam O, Carvalho TG, Cohen SR, Sharon M, Regev-Rudzki N. Dekel E, et al. Among authors: rotkopf r. Nat Commun. 2021 Feb 19;12(1):1172. doi: 10.1038/s41467-021-21344-8. Nat Commun. 2021. PMID: 33608523 Free PMC article.
Malaria parasites both repress host CXCL10 and use it as a cue for growth acceleration.
Ofir-Birin Y, Ben Ami Pilo H, Cruz Camacho A, Rudik A, Rivkin A, Revach OY, Nir N, Block Tamin T, Abou Karam P, Kiper E, Peleg Y, Nevo R, Solomon A, Havkin-Solomon T, Rojas A, Rotkopf R, Porat Z, Avni D, Schwartz E, Zillinger T, Hartmann G, Di Pizio A, Quashie NB, Dikstein R, Gerlic M, Torrecilhas AC, Levy C, Nolte-'t Hoen ENM, Bowie AG, Regev-Rudzki N. Ofir-Birin Y, et al. Among authors: rotkopf r. Nat Commun. 2021 Aug 11;12(1):4851. doi: 10.1038/s41467-021-24997-7. Nat Commun. 2021. PMID: 34381047 Free PMC article.
Malaria parasites release vesicle subpopulations with signatures of different destinations.
Abou Karam P, Rosenhek-Goldian I, Ziv T, Ben Ami Pilo H, Azuri I, Rivkin A, Kiper E, Rotkopf R, Cohen SR, Torrecilhas AC, Avinoam O, Rojas A, Morandi MI, Regev-Rudzki N. Abou Karam P, et al. Among authors: rotkopf r. EMBO Rep. 2022 Jul 5;23(7):e54755. doi: 10.15252/embr.202254755. Epub 2022 Jun 1. EMBO Rep. 2022. PMID: 35642585 Free PMC article.
High-throughput analysis of the transcriptional patterns of sexual genes in malaria.
Cruz Camacho A, Kiper E, Oren S, Zaharoni N, Nir N, Soffer N, Noy Y, Ben David B, Rivkin A, Rotkopf R, Michael D, Carvalho TG, Regev-Rudzki N. Cruz Camacho A, et al. Among authors: rotkopf r. Parasit Vectors. 2023 Jan 13;16(1):14. doi: 10.1186/s13071-022-05624-w. Parasit Vectors. 2023. PMID: 36639683 Free PMC article.
Piezo2 expressed in proprioceptive neurons is essential for skeletal integrity.
Assaraf E, Blecher R, Heinemann-Yerushalmi L, Krief S, Carmel Vinestock R, Biton IE, Brumfeld V, Rotkopf R, Avisar E, Agar G, Zelzer E. Assaraf E, et al. Among authors: rotkopf r. Nat Commun. 2020 Jun 23;11(1):3168. doi: 10.1038/s41467-020-16971-6. Nat Commun. 2020. PMID: 32576830 Free PMC article.
Identification of bacteria-derived HLA-bound peptides in melanoma.
Kalaora S, Nagler A, Nejman D, Alon M, Barbolin C, Barnea E, Ketelaars SLC, Cheng K, Vervier K, Shental N, Bussi Y, Rotkopf R, Levy R, Benedek G, Trabish S, Dadosh T, Levin-Zaidman S, Geller LT, Wang K, Greenberg P, Yagel G, Peri A, Fuks G, Bhardwaj N, Reuben A, Hermida L, Johnson SB, Galloway-Peña JR, Shropshire WC, Bernatchez C, Haymaker C, Arora R, Roitman L, Eilam R, Weinberger A, Lotan-Pompan M, Lotem M, Admon A, Levin Y, Lawley TD, Adams DJ, Levesque MP, Besser MJ, Schachter J, Golani O, Segal E, Geva-Zatorsky N, Ruppin E, Kvistborg P, Peterson SN, Wargo JA, Straussman R, Samuels Y. Kalaora S, et al. Among authors: rotkopf r. Nature. 2021 Apr;592(7852):138-143. doi: 10.1038/s41586-021-03368-8. Epub 2021 Mar 17. Nature. 2021. PMID: 33731925 Free PMC article.
BLM helicase protein negatively regulates stress granule formation through unwinding RNA G-quadruplex structures.
Danino YM, Molitor L, Rosenbaum-Cohen T, Kaiser S, Cohen Y, Porat Z, Marmor-Kollet H, Katina C, Savidor A, Rotkopf R, Ben-Isaac E, Golani O, Levin Y, Monchaud D, Hickson ID, Hornstein E. Danino YM, et al. Among authors: rotkopf r. Nucleic Acids Res. 2023 Sep 22;51(17):9369-9384. doi: 10.1093/nar/gkad613. Nucleic Acids Res. 2023. PMID: 37503837 Free PMC article.
48 results