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Eighteen-Year Disease Progression and Survival in CADASIL.
Gravesteijn G, Hack RJ, Opstal AMV, van Eijsden BJ, Middelkoop HAM, Rodriguez Girondo MDM, Aartsma-Rus A, Grond JV, Rutten JW, Oberstein SAJL. Gravesteijn G, et al. J Stroke. 2021 Jan;23(1):132-134. doi: 10.5853/jos.2020.04112. Epub 2021 Jan 31. J Stroke. 2021. PMID: 33600711 Free PMC article. No abstract available.
The NOTCH3 score: a pre-clinical CADASIL biomarker in a novel human genomic NOTCH3 transgenic mouse model with early progressive vascular NOTCH3 accumulation.
Rutten JW, Klever RR, Hegeman IM, Poole DS, Dauwerse HG, Broos LA, Breukel C, Aartsma-Rus AM, Verbeek JS, van der Weerd L, van Duinen SG, van den Maagdenberg AM, Lesnik Oberstein SA. Rutten JW, et al. Acta Neuropathol Commun. 2015 Dec 29;3:89. doi: 10.1186/s40478-015-0268-1. Acta Neuropathol Commun. 2015. PMID: 26715087 Free PMC article.
Serum Neurofilament light correlates with CADASIL disease severity and survival.
Gravesteijn G, Rutten JW, Verberk IMW, Böhringer S, Liem MK, van der Grond J, Aartsma-Rus A, Teunissen CE, Lesnik Oberstein SAJ. Gravesteijn G, et al. Ann Clin Transl Neurol. 2018 Nov 20;6(1):46-56. doi: 10.1002/acn3.678. eCollection 2019 Jan. Ann Clin Transl Neurol. 2018. PMID: 30656183 Free PMC article.
Progression and Classification of Granular Osmiophilic Material (GOM) Deposits in Functionally Characterized Human NOTCH3 Transgenic Mice.
Gravesteijn G, Munting LP, Overzier M, Mulder AA, Hegeman I, Derieppe M, Koster AJ, van Duinen SG, Meijer OC, Aartsma-Rus A, van der Weerd L, Jost CR, van den Maagdenberg AMJM, Rutten JW, Lesnik Oberstein SAJ. Gravesteijn G, et al. Transl Stroke Res. 2020 Jun;11(3):517-527. doi: 10.1007/s12975-019-00742-7. Epub 2019 Oct 30. Transl Stroke Res. 2020. PMID: 31667734 Free PMC article.
Peripheral blood transcriptome profiling enables monitoring disease progression in dystrophic mice and patients.
Signorelli M, Ebrahimpoor M, Veth O, Hettne K, Verwey N, García-Rodríguez R, Tanganyika-deWinter CL, Lopez Hernandez LB, Escobar Cedillo R, Gómez Díaz B, Magnusson OT, Mei H, Tsonaka R, Aartsma-Rus A, Spitali P. Signorelli M, et al. EMBO Mol Med. 2021 Apr 9;13(4):e13328. doi: 10.15252/emmm.202013328. Epub 2021 Mar 10. EMBO Mol Med. 2021. PMID: 33751844 Free PMC article.
253 results