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Biogeographical venom variation in the Indian spectacled cobra (Naja naja) underscores the pressing need for pan-India efficacious snakebite therapy.
Senji Laxme RR, Attarde S, Khochare S, Suranse V, Martin G, Casewell NR, Whitaker R, Sunagar K. Senji Laxme RR, et al. Among authors: casewell nr. PLoS Negl Trop Dis. 2021 Feb 18;15(2):e0009150. doi: 10.1371/journal.pntd.0009150. eCollection 2021 Feb. PLoS Negl Trop Dis. 2021. PMID: 33600405 Free PMC article.
Widespread convergence in toxin resistance by predictable molecular evolution.
Ujvari B, Casewell NR, Sunagar K, Arbuckle K, Wüster W, Lo N, O'Meally D, Beckmann C, King GF, Deplazes E, Madsen T. Ujvari B, et al. Among authors: casewell nr. Proc Natl Acad Sci U S A. 2015 Sep 22;112(38):11911-6. doi: 10.1073/pnas.1511706112. Epub 2015 Sep 8. Proc Natl Acad Sci U S A. 2015. PMID: 26372961 Free PMC article.
Preclinical antivenom-efficacy testing reveals potentially disturbing deficiencies of snakebite treatment capability in East Africa.
Harrison RA, Oluoch GO, Ainsworth S, Alsolaiss J, Bolton F, Arias AS, Gutiérrez JM, Rowley P, Kalya S, Ozwara H, Casewell NR. Harrison RA, et al. Among authors: casewell nr. PLoS Negl Trop Dis. 2017 Oct 18;11(10):e0005969. doi: 10.1371/journal.pntd.0005969. eCollection 2017 Oct. PLoS Negl Trop Dis. 2017. PMID: 29045429 Free PMC article.
Evaluation of the geographical utility of Eastern Russell's viper (Daboia siamensis) antivenom from Thailand and an assessment of its protective effects against venom-induced nephrotoxicity.
Chaisakul J, Alsolaiss J, Charoenpitakchai M, Wiwatwarayos K, Sookprasert N, Harrison RA, Chaiyabutr N, Chanhome L, Tan CH, Casewell NR. Chaisakul J, et al. Among authors: casewell nr. PLoS Negl Trop Dis. 2019 Oct 23;13(10):e0007338. doi: 10.1371/journal.pntd.0007338. eCollection 2019 Oct. PLoS Negl Trop Dis. 2019. PMID: 31644526 Free PMC article.
Solenodon genome reveals convergent evolution of venom in eulipotyphlan mammals.
Casewell NR, Petras D, Card DC, Suranse V, Mychajliw AM, Richards D, Koludarov I, Albulescu LO, Slagboom J, Hempel BF, Ngum NM, Kennerley RJ, Brocca JL, Whiteley G, Harrison RA, Bolton FMS, Debono J, Vonk FJ, Alföldi J, Johnson J, Karlsson EK, Lindblad-Toh K, Mellor IR, Süssmuth RD, Fry BG, Kuruppu S, Hodgson WC, Kool J, Castoe TA, Barnes I, Sunagar K, Undheim EAB, Turvey ST. Casewell NR, et al. Proc Natl Acad Sci U S A. 2019 Dec 17;116(51):25745-25755. doi: 10.1073/pnas.1906117116. Epub 2019 Nov 26. Proc Natl Acad Sci U S A. 2019. PMID: 31772017 Free PMC article.
Causes and Consequences of Snake Venom Variation.
Casewell NR, Jackson TNW, Laustsen AH, Sunagar K. Casewell NR, et al. Trends Pharmacol Sci. 2020 Aug;41(8):570-581. doi: 10.1016/j.tips.2020.05.006. Epub 2020 Jun 19. Trends Pharmacol Sci. 2020. PMID: 32564899 Free PMC article. Review.
An interactive database for the investigation of high-density peptide microarray guided interaction patterns and antivenom cross-reactivity.
Krause KE, Jenkins TP, Skaarup C, Engmark M, Casewell NR, Ainsworth S, Lomonte B, Fernández J, Gutiérrez JM, Lund O, Laustsen AH. Krause KE, et al. Among authors: casewell nr. PLoS Negl Trop Dis. 2020 Jun 24;14(6):e0008366. doi: 10.1371/journal.pntd.0008366. eCollection 2020 Jun. PLoS Negl Trop Dis. 2020. PMID: 32579606 Free PMC article.
An analysis of preclinical efficacy testing of antivenoms for sub-Saharan Africa: Inadequate independent scrutiny and poor-quality reporting are barriers to improving snakebite treatment and management.
Ainsworth S, Menzies SK, Casewell NR, Harrison RA. Ainsworth S, et al. Among authors: casewell nr. PLoS Negl Trop Dis. 2020 Aug 20;14(8):e0008579. doi: 10.1371/journal.pntd.0008579. eCollection 2020 Aug. PLoS Negl Trop Dis. 2020. PMID: 32817682 Free PMC article.
148 results