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Increased Mortality in Patients With Preoperative and Persistent Postoperative Pulmonary Hypertension Undergoing Mitral Valve Surgery for Mitral Regurgitation: A Cohort Study.
Genuardi MV, Shpilsky D, Handen A, VanSpeybroeck G, Canterbury A, Lu M, Shapero K, Nieves RA, Thoma F, Mulukutla SR, Cavalcante JL, Chan SY. Genuardi MV, et al. Among authors: chan sy. J Am Heart Assoc. 2021 Feb;10(5):e018394. doi: 10.1161/JAHA.120.018394. Epub 2021 Feb 18. J Am Heart Assoc. 2021. PMID: 33599144 Free PMC article.
p62/SQSTM1 Cooperates with Hyperactive mTORC1 to Regulate Glutathione Production, Maintain Mitochondrial Integrity, and Promote Tumorigenesis.
Lam HC, Baglini CV, Lope AL, Parkhitko AA, Liu HJ, Alesi N, Malinowska IA, Ebrahimi-Fakhari D, Saffari A, Yu JJ, Pereira A, Khabibullin D, Ogorek B, Nijmeh J, Kavanagh T, Handen A, Chan SY, Asara JM, Oldham WM, Diaz-Meco MT, Moscat J, Sahin M, Priolo C, Henske EP. Lam HC, et al. Among authors: chan sy. Cancer Res. 2017 Jun 15;77(12):3255-3267. doi: 10.1158/0008-5472.CAN-16-2458. Epub 2017 May 16. Cancer Res. 2017. PMID: 28512249 Free PMC article.
Outcomes of persistent pulmonary hypertension following transcatheter aortic valve replacement.
Masri A, Abdelkarim I, Sharbaugh MS, Althouse AD, Xu J, Han W, Chan SY, Katz WE, Crock FW, Harinstein ME, Kliner DE, Navid F, Lee JS, Gleason TG, Schindler JT, Cavalcante JL. Masri A, et al. Among authors: chan sy. Heart. 2018 May;104(10):821-827. doi: 10.1136/heartjnl-2017-311978. Epub 2017 Sep 29. Heart. 2018. PMID: 28970276 Free PMC article.
Rapamycin-induced miR-21 promotes mitochondrial homeostasis and adaptation in mTORC1 activated cells.
Lam HC, Liu HJ, Baglini CV, Filippakis H, Alesi N, Nijmeh J, Du H, Lope AL, Cottrill KA, Handen A, Asara JM, Kwiatkowski DJ, Ben-Sahra I, Oldham WM, Chan SY, Henske EP. Lam HC, et al. Among authors: chan sy. Oncotarget. 2017 Aug 4;8(39):64714-64727. doi: 10.18632/oncotarget.19947. eCollection 2017 Sep 12. Oncotarget. 2017. PMID: 29029388 Free PMC article.
Systems Analysis of the Human Pulmonary Arterial Hypertension Lung Transcriptome.
Stearman RS, Bui QM, Speyer G, Handen A, Cornelius AR, Graham BB, Kim S, Mickler EA, Tuder RM, Chan SY, Geraci MW. Stearman RS, et al. Among authors: chan sy. Am J Respir Cell Mol Biol. 2019 Jun;60(6):637-649. doi: 10.1165/rcmb.2018-0368OC. Am J Respir Cell Mol Biol. 2019. PMID: 30562042 Free PMC article.
The Search for Disease-Modifying Therapies in Pulmonary Hypertension.
Woodcock CC, Chan SY. Woodcock CC, et al. Among authors: chan sy. J Cardiovasc Pharmacol Ther. 2019 Jul;24(4):334-354. doi: 10.1177/1074248419829172. Epub 2019 Feb 17. J Cardiovasc Pharmacol Ther. 2019. PMID: 30773044 Free PMC article. Review.
Distinct plasma gradients of microRNA-204 in the pulmonary circulation of patients suffering from WHO Groups I and II pulmonary hypertension.
Estephan LE, Genuardi MV, Kosanovich CM, Risbano MG, Zhang Y, Petro N, Watson A, Al Aaraj Y, Sembrat JC, Rojas M, Goncharov DA, Simon MA, Goncharova EA, Vaidya A, Smith A, Mazurek J, Han Y, Chan SY. Estephan LE, et al. Among authors: chan sy. Pulm Circ. 2019 Apr-Jun;9(2):2045894019840646. doi: 10.1177/2045894019840646. Pulm Circ. 2019. PMID: 30854934 Free PMC article.
1,076 results