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HAT cofactor TRRAP modulates microtubule dynamics via SP1 signaling to prevent neurodegeneration.
Elife. 2021 Feb 17;10:e61531. doi: 10.7554/eLife.61531.
Elife. 2021.
PMID: 33594975
Free PMC article.
Reduced proteasome activity in the aging brain results in ribosome stoichiometry loss and aggregation.
Kelmer Sacramento E, Kirkpatrick JM, Mazzetto M, Baumgart M, Bartolome A, Di Sanzo S, Caterino C, Sanguanini M, Papaevgeniou N, Lefaki M, Childs D, Bagnoli S, Terzibasi Tozzini E, Di Fraia D, Romanov N, Sudmant PH, Huber W, Chondrogianni N, Vendruscolo M, Cellerino A, Ori A.
Kelmer Sacramento E, et al.
Mol Syst Biol. 2020 Jun;16(6):e9596. doi: 10.15252/msb.20209596.
Mol Syst Biol. 2020.
PMID: 32558274
Free PMC article.
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Impact of inflammatory preconditioning on murine microglial proteome response induced by focal ischemic brain injury.
Helbing DL, Haas F, Cirri E, Rahnis N, Dau TTD, Kelmer Sacramento E, Oraha N, Böhm L, Lajqi T, Fehringer P, Morrison H, Bauer R.
Helbing DL, et al. Among authors: kelmer sacramento e.
Front Immunol. 2024 Apr 9;15:1227355. doi: 10.3389/fimmu.2024.1227355. eCollection 2024.
Front Immunol. 2024.
PMID: 38655254
Free PMC article.
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Impaired biogenesis of basic proteins impacts multiple hallmarks of the aging brain.
Di Fraia D, Marino A, Lee JH, Kelmer Sacramento E, Baumgart M, Bagnoli S, Tomaz da Silva P, Kumar Sahu A, Siano G, Tiessen M, Terzibasi-Tozzini E, Gagneur J, Frydman J, Cellerino A, Ori A.
Di Fraia D, et al. Among authors: kelmer sacramento e.
bioRxiv [Preprint]. 2024 Jan 9:2023.07.20.549210. doi: 10.1101/2023.07.20.549210.
bioRxiv. 2024.
PMID: 38260253
Free PMC article.
Preprint.
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Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD.
Seddighi S, Qi YA, Brown AL, Wilkins OG, Bereda C, Belair C, Zhang Y, Prudencio M, Keuss MJ, Khandeshi A, Pickles S, Hill SE, Hawrot J, Ramos DM, Yuan H, Roberts J, Kelmer Sacramento E, Shah SI, Nalls MA, Colon-Mercado J, Reyes JF, Ryan VH, Nelson MP, Cook C, Li Z, Screven L, Kwan JY, Shantaraman A, Ping L, Koike Y, Oskarsson B, Staff N, Duong DM, Ahmed A, Secrier M, Ule J, Jacobson S, Rohrer J, Malaspina A, Glass JD, Ori A, Seyfried NT, Maragkakis M, Petrucelli L, Fratta P, Ward ME.
Seddighi S, et al. Among authors: kelmer sacramento e.
bioRxiv [Preprint]. 2023 Jan 23:2023.01.23.525149. doi: 10.1101/2023.01.23.525149.
bioRxiv. 2023.
PMID: 36747793
Free PMC article.
Updated.
Preprint.
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