Puigserver P - Search Results

1

A cold-stress-inducible PERK/OGT axis controls TOM70-assisted mitochondrial protein import and cristae formation.

Latorre-Muro P, O'Malley KE, Bennett CF, Perry EA, Balsa E, Tavares CDJ, Jedrychowski M, Gygi SP, Puigserver P. Latorre-Muro P, et al. Among authors: puigserver p. Cell Metab. 2021 Mar 2;33(3):598-614.e7. doi: 10.1016/j.cmet.2021.01.013. Epub 2021 Feb 15. Cell Metab. 2021. PMID: 33592173 Free PMC article.

2

A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis.

Puigserver P, Wu Z, Park CW, Graves R, Wright M, Spiegelman BM. Puigserver P, et al. Cell. 1998 Mar 20;92(6):829-39. doi: 10.1016/s0092-8674(00)81410-5. Cell. 1998. PMID: 9529258 Free article.

3

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1.

Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM, Puigserver P. Rodgers JT, et al. Among authors: puigserver p. Nature. 2005 Mar 3;434(7029):113-8. doi: 10.1038/nature03354. Nature. 2005. PMID: 15744310

4

GCN5-mediated transcriptional control of the metabolic coactivator PGC-1beta through lysine acetylation.

Kelly TJ, Lerin C, Haas W, Gygi SP, Puigserver P. Kelly TJ, et al. Among authors: puigserver p. J Biol Chem. 2009 Jul 24;284(30):19945-52. doi: 10.1074/jbc.M109.015164. Epub 2009 Jun 2. J Biol Chem. 2009. PMID: 19491097 Free PMC article.

5

Cdc2-like kinase 2 is an insulin-regulated suppressor of hepatic gluconeogenesis.

Rodgers JT, Haas W, Gygi SP, Puigserver P. Rodgers JT, et al. Among authors: puigserver p. Cell Metab. 2010 Jan;11(1):23-34. doi: 10.1016/j.cmet.2009.11.006. Cell Metab. 2010. PMID: 20074525 Free PMC article.

6

The cAMP/PKA pathway rapidly activates SIRT1 to promote fatty acid oxidation independently of changes in NAD(+).

Gerhart-Hines Z, Dominy JE Jr, Blättler SM, Jedrychowski MP, Banks AS, Lim JH, Chim H, Gygi SP, Puigserver P. Gerhart-Hines Z, et al. Among authors: puigserver p. Mol Cell. 2011 Dec 23;44(6):851-63. doi: 10.1016/j.molcel.2011.12.005. Mol Cell. 2011. PMID: 22195961 Free PMC article.

7

Yin Yang 1 deficiency in skeletal muscle protects against rapamycin-induced diabetic-like symptoms through activation of insulin/IGF signaling.

Blättler SM, Cunningham JT, Verdeguer F, Chim H, Haas W, Liu H, Romanino K, Rüegg MA, Gygi SP, Shi Y, Puigserver P. Blättler SM, et al. Among authors: puigserver p. Cell Metab. 2012 Apr 4;15(4):505-17. doi: 10.1016/j.cmet.2012.03.008. Cell Metab. 2012. PMID: 22482732 Free PMC article.

8

The deacetylase Sirt6 activates the acetyltransferase GCN5 and suppresses hepatic gluconeogenesis.

Dominy JE Jr, Lee Y, Jedrychowski MP, Chim H, Jurczak MJ, Camporez JP, Ruan HB, Feldman J, Pierce K, Mostoslavsky R, Denu JM, Clish CB, Yang X, Shulman GI, Gygi SP, Puigserver P. Dominy JE Jr, et al. Among authors: puigserver p. Mol Cell. 2012 Dec 28;48(6):900-13. doi: 10.1016/j.molcel.2012.09.030. Epub 2012 Nov 8. Mol Cell. 2012. PMID: 23142079 Free PMC article.

9

Cdc2-like kinase 2 suppresses hepatic fatty acid oxidation and ketogenesis through disruption of the PGC-1α and MED1 complex.

Tabata M, Rodgers JT, Hall JA, Lee Y, Jedrychowski MP, Gygi SP, Puigserver P. Tabata M, et al. Among authors: puigserver p. Diabetes. 2014 May;63(5):1519-32. doi: 10.2337/db13-1304. Epub 2014 Jan 23. Diabetes. 2014. PMID: 24458359 Free PMC article.

10

Molecular pathophysiology of hepatic glucose production.

Sharabi K, Tavares CD, Rines AK, Puigserver P. Sharabi K, et al. Among authors: puigserver p. Mol Aspects Med. 2015 Dec;46:21-33. doi: 10.1016/j.mam.2015.09.003. Epub 2015 Nov 5. Mol Aspects Med. 2015. PMID: 26549348 Free PMC article. Review.

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