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Discovery of remogliflozin etabonate: A potent and highly selective SGLT2 inhibitor.
Shimizu K, Fujikura H, Fushimi N, Nishimura T, Tatani K, Katsuno K, Fujimori Y, Watanabe S, Hiratochi M, Nakabayashi T, Kamada N, Arakawa K, Hikawa H, Azumaya I, Isaji M. Shimizu K, et al. Among authors: fujimori y. Bioorg Med Chem. 2021 Mar 15;34:116033. doi: 10.1016/j.bmc.2021.116033. Epub 2021 Jan 22. Bioorg Med Chem. 2021. PMID: 33581390
Sergliflozin, a novel selective inhibitor of low-affinity sodium glucose cotransporter (SGLT2), validates the critical role of SGLT2 in renal glucose reabsorption and modulates plasma glucose level.
Katsuno K, Fujimori Y, Takemura Y, Hiratochi M, Itoh F, Komatsu Y, Fujikura H, Isaji M. Katsuno K, et al. Among authors: fujimori y. J Pharmacol Exp Ther. 2007 Jan;320(1):323-30. doi: 10.1124/jpet.106.110296. Epub 2006 Oct 18. J Pharmacol Exp Ther. 2007. PMID: 17050778
330 results