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491 results

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Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes.
Zang ZJ, Cutcutache I, Poon SL, Zhang SL, McPherson JR, Tao J, Rajasegaran V, Heng HL, Deng N, Gan A, Lim KH, Ong CK, Huang D, Chin SY, Tan IB, Ng CC, Yu W, Wu Y, Lee M, Wu J, Poh D, Wan WK, Rha SY, So J, Salto-Tellez M, Yeoh KG, Wong WK, Zhu YJ, Futreal PA, Pang B, Ruan Y, Hillmer AM, Bertrand D, Nagarajan N, Rozen S, Teh BT, Tan P. Zang ZJ, et al. Among authors: teh bt. Nat Genet. 2012 May;44(5):570-4. doi: 10.1038/ng.2246. Nat Genet. 2012. PMID: 22484628
Nanoscale chromatin profiling of gastric adenocarcinoma reveals cancer-associated cryptic promoters and somatically acquired regulatory elements.
Muratani M, Deng N, Ooi WF, Lin SJ, Xing M, Xu C, Qamra A, Tay ST, Malik S, Wu J, Lee MH, Zhang S, Tan LL, Chua H, Wong WK, Ong HS, Ooi LL, Chow PK, Chan WH, Soo KC, Goh LK, Rozen S, Teh BT, Yu Q, Ng HH, Tan P. Muratani M, et al. Among authors: teh bt. Nat Commun. 2014 Jul 10;5:4361. doi: 10.1038/ncomms5361. Nat Commun. 2014. PMID: 25008978 Free article.
Exome sequencing identifies highly recurrent MED12 somatic mutations in breast fibroadenoma.
Lim WK, Ong CK, Tan J, Thike AA, Ng CC, Rajasegaran V, Myint SS, Nagarajan S, Nasir ND, McPherson JR, Cutcutache I, Poore G, Tay ST, Ooi WS, Tan VK, Hartman M, Ong KW, Tan BK, Rozen SG, Tan PH, Tan P, Teh BT. Lim WK, et al. Among authors: teh bt. Nat Genet. 2014 Aug;46(8):877-80. doi: 10.1038/ng.3037. Epub 2014 Jul 20. Nat Genet. 2014. PMID: 25038752
Regulatory crosstalk between lineage-survival oncogenes KLF5, GATA4 and GATA6 cooperatively promotes gastric cancer development.
Chia NY, Deng N, Das K, Huang D, Hu L, Zhu Y, Lim KH, Lee MH, Wu J, Sam XX, Tan GS, Wan WK, Yu W, Gan A, Tan AL, Tay ST, Soo KC, Wong WK, Dominguez LT, Ng HH, Rozen S, Goh LK, Teh BT, Tan P. Chia NY, et al. Among authors: teh bt. Gut. 2015 May;64(5):707-19. doi: 10.1136/gutjnl-2013-306596. Epub 2014 Jul 22. Gut. 2015. PMID: 25053715
MED12 is frequently mutated in breast phyllodes tumours: a study of 112 cases.
Ng CC, Tan J, Ong CK, Lim WK, Rajasegaran V, Nasir ND, Lim JC, Thike AA, Salahuddin SA, Iqbal J, Busmanis I, Chong AP, Teh BT, Tan PH. Ng CC, et al. Among authors: teh bt. J Clin Pathol. 2015 Sep;68(9):685-91. doi: 10.1136/jclinpath-2015-202896. Epub 2015 May 27. J Clin Pathol. 2015. PMID: 26018969
SETD2 histone modifier loss in aggressive GI stromal tumours.
Huang KK, McPherson JR, Tay ST, Das K, Tan IB, Ng CC, Chia NY, Zhang SL, Myint SS, Hu L, Rajasegaran V, Huang D, Loh JL, Gan A, Sairi AN, Sam XX, Dominguez LT, Lee M, Soo KC, Ooi LL, Ong HS, Chung A, Chow PK, Wong WK, Selvarajan S, Ong CK, Lim KH, Nandi T, Rozen S, Teh BT, Quek R, Tan P. Huang KK, et al. Among authors: teh bt. Gut. 2016 Dec;65(12):1960-1972. doi: 10.1136/gutjnl-2015-309482. Epub 2015 Sep 3. Gut. 2016. PMID: 26338826
Whole-exome sequencing of breast cancer, malignant peripheral nerve sheath tumor and neurofibroma from a patient with neurofibromatosis type 1.
McPherson JR, Ong CK, Ng CC, Rajasegaran V, Heng HL, Yu WS, Tan BK, Madhukumar P, Teo MC, Ngeow J, Thike AA, Rozen SG, Tan PH, Lee AS, Teh BT, Yap YS. McPherson JR, et al. Among authors: teh bt. Cancer Med. 2015 Dec;4(12):1871-8. doi: 10.1002/cam4.551. Epub 2015 Oct 3. Cancer Med. 2015. PMID: 26432421 Free PMC article.
491 results