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Prostaglandin E2 promotes intestinal inflammation via inhibiting microbiota-dependent regulatory T cells.
Crittenden S, Goepp M, Pollock J, Robb CT, Smyth DJ, Zhou Y, Andrews R, Tyrrell V, Gkikas K, Adima A, O'Connor RA, Davies L, Li XF, Yao HX, Ho GT, Zheng X, Mair A, Vermeren S, Qian BZ, Mole DJ, Gerasimidis K, Schwarze JKJ, Breyer RM, Arends MJ, O'Donnell VB, Iredale JP, Anderton SM, Narumiya S, Maizels RM, Rossi AG, Howie SE, Yao C. Crittenden S, et al. Among authors: tyrrell v. Sci Adv. 2021 Feb 12;7(7):eabd7954. doi: 10.1126/sciadv.abd7954. Print 2021 Feb. Sci Adv. 2021. PMID: 33579710 Free PMC article.
Phospholipid membranes drive abdominal aortic aneurysm development through stimulating coagulation factor activity.
Allen-Redpath K, Aldrovandi M, Lauder SN, Gketsopoulou A, Tyrrell VJ, Slatter DA, Andrews R, Watkins WJ, Atkinson G, McNeill E, Gilfedder A, Protty M, Burston J, Johnson SRC, Rodrigues PRS, Jones DO, Lee R, Handa A, Channon K, Obaji S, Alvarez-Jarreta J, Krönke G, Ackermann J, Jenkins PV, Collins PW, O'Donnell VB. Allen-Redpath K, et al. Proc Natl Acad Sci U S A. 2019 Apr 16;116(16):8038-8047. doi: 10.1073/pnas.1814409116. Epub 2019 Apr 3. Proc Natl Acad Sci U S A. 2019. PMID: 30944221 Free PMC article.
Dihomo-γ-linolenic acid inhibits several key cellular processes associated with atherosclerosis.
Gallagher H, Williams JO, Ferekidis N, Ismail A, Chan YH, Michael DR, Guschina IA, Tyrrell VJ, O'Donnell VB, Harwood JL, Khozin-Goldberg I, Boussiba S, Ramji DP. Gallagher H, et al. Biochim Biophys Acta Mol Basis Dis. 2019 Sep 1;1865(9):2538-2550. doi: 10.1016/j.bbadis.2019.06.011. Epub 2019 Jun 13. Biochim Biophys Acta Mol Basis Dis. 2019. PMID: 31202985 Free PMC article.
Metabolic Dysregulation of the Lysophospholipid/Autotaxin Axis in the Chromosome 9p21 Gene SNP rs10757274.
Meckelmann SW, Hawksworth JI, White D, Andrews R, Rodrigues P, O'Connor A, Alvarez-Jarreta J, Tyrrell VJ, Hinz C, Zhou Y, Williams J, Aldrovandi M, Watkins WJ, Engler AJ, Lo Sardo V, Slatter DA, Allen SM, Acharya J, Mitchell J, Cooper J, Aoki J, Kano K, Humphries SE, O'Donnell VB. Meckelmann SW, et al. Among authors: tyrrell vj. Circ Genom Precis Med. 2020 Jun;13(3):e002806. doi: 10.1161/CIRCGEN.119.002806. Epub 2020 May 12. Circ Genom Precis Med. 2020. PMID: 32396387 Free PMC article.
52 results