Mole DJ - Search Results

1

Prostaglandin E₂ promotes intestinal inflammation via inhibiting microbiota-dependent regulatory T cells.

Crittenden S, Goepp M, Pollock J, Robb CT, Smyth DJ, Zhou Y, Andrews R, Tyrrell V, Gkikas K, Adima A, O'Connor RA, Davies L, Li XF, Yao HX, Ho GT, Zheng X, Mair A, Vermeren S, Qian BZ, Mole DJ, Gerasimidis K, Schwarze JKJ, Breyer RM, Arends MJ, O'Donnell VB, Iredale JP, Anderton SM, Narumiya S, Maizels RM, Rossi AG, Howie SE, Yao C. Crittenden S, et al. Among authors: mole dj. Sci Adv. 2021 Feb 12;7(7):eabd7954. doi: 10.1126/sciadv.abd7954. Print 2021 Feb. Sci Adv. 2021. PMID: 33579710 Free PMC article.

2

Alcohol and global health: focus on acute pancreatitis needed.

Mole D, Garden OJ, Iredale J. Mole D, et al. Lancet. 2009 Sep 19;374(9694):976-977. doi: 10.1016/S0140-6736(09)61659-7. Lancet. 2009. PMID: 19766877 No abstract available.

3

Relaxin modulates human and rat hepatic myofibroblast function and ameliorates portal hypertension in vivo.

Fallowfield JA, Hayden AL, Snowdon VK, Aucott RL, Stutchfield BM, Mole DJ, Pellicoro A, Gordon-Walker TT, Henke A, Schrader J, Trivedi PJ, Princivalle M, Forbes SJ, Collins JE, Iredale JP. Fallowfield JA, et al. Among authors: mole dj. Hepatology. 2014 Apr;59(4):1492-504. doi: 10.1002/hep.26627. Epub 2014 Mar 3. Hepatology. 2014. PMID: 23873655

4

Bacterial expression of human kynurenine 3-monooxygenase: solubility, activity, purification.

Wilson K, Mole DJ, Binnie M, Homer NZ, Zheng X, Yard BA, Iredale JP, Auer M, Webster SP. Wilson K, et al. Among authors: mole dj. Protein Expr Purif. 2014 Mar;95(100):96-103. doi: 10.1016/j.pep.2013.11.015. Epub 2013 Dec 4. Protein Expr Purif. 2014. PMID: 24316190 Free PMC article.

5

The intestinal mucus layer is a critical component of the gut barrier that is damaged during acute pancreatitis.

Fishman JE, Levy G, Alli V, Zheng X, Mole DJ, Deitch EA. Fishman JE, et al. Among authors: mole dj. Shock. 2014 Sep;42(3):264-70. doi: 10.1097/SHK.0000000000000209. Shock. 2014. PMID: 24978882 Free PMC article.

6

A magnetic bead-based ligand binding assay to facilitate human kynurenine 3-monooxygenase drug discovery.

Wilson K, Mole DJ, Homer NZ, Iredale JP, Auer M, Webster SP. Wilson K, et al. Among authors: mole dj. J Biomol Screen. 2015 Feb;20(2):292-8. doi: 10.1177/1087057114554171. Epub 2014 Oct 8. J Biomol Screen. 2015. PMID: 25296660

7

Prostaglandin E₂ constrains systemic inflammation through an innate lymphoid cell-IL-22 axis.

Duffin R, O'Connor RA, Crittenden S, Forster T, Yu C, Zheng X, Smyth D, Robb CT, Rossi F, Skouras C, Tang S, Richards J, Pellicoro A, Weller RB, Breyer RM, Mole DJ, Iredale JP, Anderton SM, Narumiya S, Maizels RM, Ghazal P, Howie SE, Rossi AG, Yao C. Duffin R, et al. Among authors: mole dj. Science. 2016 Mar 18;351(6279):1333-8. doi: 10.1126/science.aad9903. Science. 2016. PMID: 26989254 Free PMC article.

8

Overexpression of human kynurenine-3-monooxygenase protects against 3-hydroxykynurenine-mediated apoptosis through bidirectional nonlinear feedback.

Wilson K, Auer M, Binnie M, Zheng X, Pham NT, Iredale JP, Webster SP, Mole DJ. Wilson K, et al. Among authors: mole dj. Cell Death Dis. 2016 Apr 14;7(4):e2197. doi: 10.1038/cddis.2016.87. Cell Death Dis. 2016. PMID: 27077813 Free PMC article.

9

Detecting drug-target binding in cells using fluorescence-activated cell sorting coupled with mass spectrometry analysis.

Wilson K, Webster SP, Iredale JP, Zheng X, Homer NZ, Pham NT, Auer M, Mole DJ. Wilson K, et al. Among authors: mole dj. Methods Appl Fluoresc. 2017 Dec 15;6(1):015002. doi: 10.1088/2050-6120/aa8c60. Methods Appl Fluoresc. 2017. PMID: 28901950 Free article.

10

Kynurenine 3-monooxygenase is a critical regulator of renal ischemia-reperfusion injury.

Zheng X, Zhang A, Binnie M, McGuire K, Webster SP, Hughes J, Howie SEM, Mole DJ. Zheng X, et al. Among authors: mole dj. Exp Mol Med. 2019 Feb 13;51(2):1-14. doi: 10.1038/s12276-019-0210-x. Exp Mol Med. 2019. PMID: 30760699 Free PMC article.

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