Lütjohann D - Search Results

1

Atxn2-CAG100-KnockIn mouse spinal cord shows progressive TDP43 pathology associated with cholesterol biosynthesis suppression.

Canet-Pons J, Sen NE, Arsović A, Almaguer-Mederos LE, Halbach MV, Key J, Döring C, Kerksiek A, Picchiarelli G, Cassel R, René F, Dieterlé S, Fuchs NV, König R, Dupuis L, Lütjohann D, Gispert S, Auburger G. Canet-Pons J, et al. Among authors: lutjohann d. Neurobiol Dis. 2021 May;152:105289. doi: 10.1016/j.nbd.2021.105289. Epub 2021 Feb 10. Neurobiol Dis. 2021. PMID: 33577922 Free article.

2

SREBP-1a polymorphism influences the risk of Alzheimer's disease in carriers of the ApoE4 allele.

Spell C, Kölsch H, Lütjohann D, Kerksiek A, Hentschel F, Damian M, von Bergmann K, Rao ML, Maier W, Heun R. Spell C, et al. Among authors: lutjohann d. Dement Geriatr Cogn Disord. 2004;18(3-4):245-9. doi: 10.1159/000080023. Epub 2004 Jul 29. Dement Geriatr Cogn Disord. 2004. PMID: 15286454

3

Insulin receptor and lipid metabolism pathology in ataxin-2 knock-out mice.

Lastres-Becker I, Brodesser S, Lütjohann D, Azizov M, Buchmann J, Hintermann E, Sandhoff K, Schürmann A, Nowock J, Auburger G. Lastres-Becker I, et al. Among authors: lutjohann d. Hum Mol Genet. 2008 May 15;17(10):1465-81. doi: 10.1093/hmg/ddn035. Epub 2008 Feb 4. Hum Mol Genet. 2008. PMID: 18250099

4

Alterations in brain cholesterol metabolism in the APPSLxPS1mut mouse, a model for Alzheimer's disease.

Vanmierlo T, Bloks VW, van Vark-van der Zee LC, Rutten K, Kerksiek A, Friedrichs S, Sijbrands E, Steinbusch HW, Kuipers F, Lütjohann D, Mulder M. Vanmierlo T, et al. Among authors: lutjohann d. J Alzheimers Dis. 2010;19(1):117-27. doi: 10.3233/JAD-2010-1209. J Alzheimers Dis. 2010. PMID: 20061631

5

Intrahepatic cholesterol influences progression, inhibition and reversal of non-alcoholic steatohepatitis in hyperlipidemic mice.

Wouters K, van Bilsen M, van Gorp PJ, Bieghs V, Lütjohann D, Kerksiek A, Staels B, Hofker MH, Shiri-Sverdlov R. Wouters K, et al. Among authors: lutjohann d. FEBS Lett. 2010 Mar 5;584(5):1001-5. doi: 10.1016/j.febslet.2010.01.046. Epub 2010 Jan 29. FEBS Lett. 2010. PMID: 20114046 Free article.

6

Dietary intake of plant sterols stably increases plant sterol levels in the murine brain.

Vanmierlo T, Weingärtner O, van der Pol S, Husche C, Kerksiek A, Friedrichs S, Sijbrands E, Steinbusch H, Grimm M, Hartmann T, Laufs U, Böhm M, de Vries HE, Mulder M, Lütjohann D. Vanmierlo T, et al. Among authors: lutjohann d. J Lipid Res. 2012 Apr;53(4):726-35. doi: 10.1194/jlr.M017244. Epub 2012 Jan 25. J Lipid Res. 2012. PMID: 22279184 Free PMC article.

7

Ursodeoxycholic acid impairs atherogenesis and promotes plaque regression by cholesterol crystal dissolution in mice.

Bode N, Grebe A, Kerksiek A, Lütjohann D, Werner N, Nickenig G, Latz E, Zimmer S. Bode N, et al. Among authors: lutjohann d. Biochem Biophys Res Commun. 2016 Sep 9;478(1):356-362. doi: 10.1016/j.bbrc.2016.07.047. Epub 2016 Jul 11. Biochem Biophys Res Commun. 2016. PMID: 27416761

8

Identification of Correlative Shifts in Indices of Brain Cholesterol Metabolism in the C57BL6/Mecp2^tm1.1Bird Mouse, a Model for Rett Syndrome.

Lütjohann D, Lopez AM, Chuang JC, Kerksiek A, Turley SD. Lütjohann D, et al. Lipids. 2018 Apr;53(4):363-373. doi: 10.1002/lipd.12041. Epub 2018 May 17. Lipids. 2018. PMID: 29770459

9

HDL inhibits endoplasmic reticulum stress-induced apoptosis of pancreatic β-cells in vitro by activation of Smoothened.

Yalcinkaya M, Kerksiek A, Gebert K, Annema W, Sibler R, Radosavljevic S, Lütjohann D, Rohrer L, von Eckardstein A. Yalcinkaya M, et al. Among authors: lutjohann d. J Lipid Res. 2020 Apr;61(4):492-504. doi: 10.1194/jlr.RA119000509. Epub 2020 Jan 6. J Lipid Res. 2020. PMID: 31907205 Free PMC article.

10

Importance of γ-secretase in the regulation of liver X receptor and cellular lipid metabolism.

Gutierrez E, Lütjohann D, Kerksiek A, Fabiano M, Oikawa N, Kuerschner L, Thiele C, Walter J. Gutierrez E, et al. Among authors: lutjohann d. Life Sci Alliance. 2020 Apr 30;3(6):e201900521. doi: 10.26508/lsa.201900521. Print 2020 Jun. Life Sci Alliance. 2020. PMID: 32354700 Free PMC article.

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