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Fine-tuning the cardiac O-GlcNAcylation regulatory enzymes governs the functional and structural phenotype of the diabetic heart.
Prakoso D, Lim SY, Erickson JR, Wallace RS, Lees JG, Tate M, Kiriazis H, Donner DG, Henstridge DC, Davey JR, Qian H, Deo M, Parry LJ, Davidoff AJ, Gregorevic P, Chatham JC, De Blasio MJ, Ritchie RH. Prakoso D, et al. Among authors: kiriazis h. Cardiovasc Res. 2022 Jan 7;118(1):212-225. doi: 10.1093/cvr/cvab043. Cardiovasc Res. 2022. PMID: 33576380
Phosphoinositide 3-kinase p110α is a master regulator of exercise-induced cardioprotection and PI3K gene therapy rescues cardiac dysfunction.
Weeks KL, Gao X, Du XJ, Boey EJ, Matsumoto A, Bernardo BC, Kiriazis H, Cemerlang N, Tan JW, Tham YK, Franke TF, Qian H, Bogoyevitch MA, Woodcock EA, Febbraio MA, Gregorevic P, McMullen JR. Weeks KL, et al. Among authors: kiriazis h. Circ Heart Fail. 2012 Jul 1;5(4):523-34. doi: 10.1161/CIRCHEARTFAILURE.112.966622. Epub 2012 Jun 15. Circ Heart Fail. 2012. PMID: 22705768
Enhanced phosphoinositide 3-kinase(p110α) activity prevents diabetes-induced cardiomyopathy and superoxide generation in a mouse model of diabetes.
Ritchie RH, Love JE, Huynh K, Bernardo BC, Henstridge DC, Kiriazis H, Tham YK, Sapra G, Qin C, Cemerlang N, Boey EJ, Jandeleit-Dahm K, Du XJ, McMullen JR. Ritchie RH, et al. Among authors: kiriazis h. Diabetologia. 2012 Dec;55(12):3369-81. doi: 10.1007/s00125-012-2720-0. Epub 2012 Sep 22. Diabetologia. 2012. PMID: 23001375
Therapeutic inhibition of the miR-34 family attenuates pathological cardiac remodeling and improves heart function.
Bernardo BC, Gao XM, Winbanks CE, Boey EJ, Tham YK, Kiriazis H, Gregorevic P, Obad S, Kauppinen S, Du XJ, Lin RC, McMullen JR. Bernardo BC, et al. Among authors: kiriazis h. Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17615-20. doi: 10.1073/pnas.1206432109. Epub 2012 Oct 9. Proc Natl Acad Sci U S A. 2012. PMID: 23047694 Free PMC article.
115 results