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Modeling, Synthesis, and Biological Evaluation of Potential Retinoid X Receptor (RXR)-Selective Agonists: Analogues of 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic Acid (Bexarotene) and 6-(Ethyl(5,5,8,8-tetrahydronaphthalen-2-yl)amino)nicotinic Acid (NEt-TMN).
Heck MC, Wagner CE, Shahani PH, MacNeill M, Grozic A, Darwaiz T, Shimabuku M, Deans DG, Robinson NM, Salama SH, Ziller JW, Ma N, van der Vaart A, Marshall PA, Jurutka PW. Heck MC, et al. J Med Chem. 2016 Oct 13;59(19):8924-8940. doi: 10.1021/acs.jmedchem.6b00812. Epub 2016 Sep 19. J Med Chem. 2016. PMID: 27592633
Inhibition of PKR by RNA and DNA viruses.
Langland JO, Cameron JM, Heck MC, Jancovich JK, Jacobs BL. Langland JO, et al. Among authors: heck mc. Virus Res. 2006 Jul;119(1):100-10. doi: 10.1016/j.virusres.2005.10.014. Epub 2006 May 15. Virus Res. 2006. PMID: 16704884 Review.
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