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An arylthiazyne derivative is a potent inhibitor of lipid peroxidation and ferroptosis providing neuroprotection in vitro and in vivo.
Keuters MH, Keksa-Goldsteine V, Dhungana H, Huuskonen MT, Pomeshchik Y, Savchenko E, Korhonen PK, Singh Y, Wojciechowski S, Lehtonen Š, Kanninen KM, Malm T, Sirviö J, Muona A, Koistinaho M, Goldsteins G, Koistinaho J. Keuters MH, et al. Among authors: pomeshchik y. Sci Rep. 2021 Feb 10;11(1):3518. doi: 10.1038/s41598-021-81741-3. Sci Rep. 2021. PMID: 33568697 Free PMC article.
Does Nrf2 gene transfer facilitate recovery after contusion spinal cord injury?
Pomeshchik Y, Kidin I, Savchenko E, Rolova T, Yamamoto M, Levonen AL, Ylä-Herttuala S, Malm T, Kanninen K, Koistinaho J. Pomeshchik Y, et al. Antioxid Redox Signal. 2014 Mar 10;20(8):1313-23. doi: 10.1089/ars.2013.5453. Epub 2013 Aug 20. Antioxid Redox Signal. 2014. PMID: 23841575
Nrf2 regulates neurogenesis and protects neural progenitor cells against Aβ toxicity.
Kärkkäinen V, Pomeshchik Y, Savchenko E, Dhungana H, Kurronen A, Lehtonen S, Naumenko N, Tavi P, Levonen AL, Yamamoto M, Malm T, Magga J, Kanninen KM, Koistinaho J. Kärkkäinen V, et al. Among authors: pomeshchik y. Stem Cells. 2014 Jul;32(7):1904-16. doi: 10.1002/stem.1666. Stem Cells. 2014. PMID: 24753106
Applications of the Keap1-Nrf2 system for gene and cell therapy.
Kanninen KM, Pomeshchik Y, Leinonen H, Malm T, Koistinaho J, Levonen AL. Kanninen KM, et al. Among authors: pomeshchik y. Free Radic Biol Med. 2015 Nov;88(Pt B):350-361. doi: 10.1016/j.freeradbiomed.2015.06.037. Epub 2015 Jul 8. Free Radic Biol Med. 2015. PMID: 26164630 Review.
Anti-inflammatory effects of ADAMTS-4 in a mouse model of ischemic stroke.
Lemarchant S, Dunghana H, Pomeshchik Y, Leinonen H, Kolosowska N, Korhonen P, Kanninen KM, García-Berrocoso T, Montaner J, Malm T, Koistinaho J. Lemarchant S, et al. Among authors: pomeshchik y. Glia. 2016 Sep;64(9):1492-507. doi: 10.1002/glia.23017. Epub 2016 Jun 15. Glia. 2016. PMID: 27301579
30 results