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Resveratrol Inhibits Aortic Root Dilatation in the Fbn1C1039G/+ Marfan Mouse Model.
Hibender S, Franken R, van Roomen C, Ter Braake A, van der Made I, Schermer EE, Gunst Q, van den Hoff MJ, Lutgens E, Pinto YM, Groenink M, Zwinderman AH, Mulder BJ, de Vries CJ, de Waard V. Hibender S, et al. Arterioscler Thromb Vasc Biol. 2016 Aug;36(8):1618-26. doi: 10.1161/ATVBAHA.116.307841. Epub 2016 Jun 9. Arterioscler Thromb Vasc Biol. 2016. PMID: 27283746 Free PMC article.
Aortic microcalcification is associated with elastin fragmentation in Marfan syndrome.
Wanga S, Hibender S, Ridwan Y, van Roomen C, Vos M, van der Made I, van Vliet N, Franken R, van Riel LA, Groenink M, Zwinderman AH, Mulder BJ, de Vries CJ, Essers J, de Waard V. Wanga S, et al. J Pathol. 2017 Nov;243(3):294-306. doi: 10.1002/path.4949. Epub 2017 Sep 21. J Pathol. 2017. PMID: 28727149 Free article.
Reducing GBA2 Activity Ameliorates Neuropathology in Niemann-Pick Type C Mice.
Marques AR, Aten J, Ottenhoff R, van Roomen CP, Herrera Moro D, Claessen N, Vinueza Veloz MF, Zhou K, Lin Z, Mirzaian M, Boot RG, De Zeeuw CI, Overkleeft HS, Yildiz Y, Aerts JM. Marques AR, et al. PLoS One. 2015 Aug 14;10(8):e0135889. doi: 10.1371/journal.pone.0135889. eCollection 2015. PLoS One. 2015. PMID: 26275242 Free PMC article.
Dyscholesterolemia Protects Against Ischemia-Induced Ventricular Arrhythmias.
Baartscheer A, Schumacher CA, Wekker V, Verkerk AO, Veldkamp MW, van Oort RJ, Elzenaar I, Ottenhoff R, van Roomen C, Aerts H, Coronel R. Baartscheer A, et al. Circ Arrhythm Electrophysiol. 2015 Dec;8(6):1481-90. doi: 10.1161/CIRCEP.115.002751. Epub 2015 Oct 1. Circ Arrhythm Electrophysiol. 2015. PMID: 26429563
Elevated globotriaosylsphingosine is a hallmark of Fabry disease.
Aerts JM, Groener JE, Kuiper S, Donker-Koopman WE, Strijland A, Ottenhoff R, van Roomen C, Mirzaian M, Wijburg FA, Linthorst GE, Vedder AC, Rombach SM, Cox-Brinkman J, Somerharju P, Boot RG, Hollak CE, Brady RO, Poorthuis BJ. Aerts JM, et al. Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):2812-7. doi: 10.1073/pnas.0712309105. Epub 2008 Feb 19. Proc Natl Acad Sci U S A. 2008. PMID: 18287059 Free PMC article.
Inhibition of glycosphingolipid synthesis induces a profound reduction of plasma cholesterol and inhibits atherosclerosis development in APOE*3 Leiden and low-density lipoprotein receptor-/- mice.
Bietrix F, Lombardo E, van Roomen CP, Ottenhoff R, Vos M, Rensen PC, Verhoeven AJ, Aerts JM, Groen AK. Bietrix F, et al. Arterioscler Thromb Vasc Biol. 2010 May;30(5):931-7. doi: 10.1161/ATVBAHA.109.201673. Epub 2010 Feb 18. Arterioscler Thromb Vasc Biol. 2010. PMID: 20167657
44 results