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Orphan nuclear receptor Nur77 affects cardiomyocyte calcium homeostasis and adverse cardiac remodelling.
Medzikovic L, Schumacher CA, Verkerk AO, van Deel ED, Wolswinkel R, van der Made I, Bleeker N, Cakici D, van den Hoogenhof MM, Meggouh F, Creemers EE, Remme CA, Baartscheer A, de Winter RJ, de Vries CJ, Arkenbout EK, de Waard V. Medzikovic L, et al. Among authors: creemers ee. Sci Rep. 2015 Oct 21;5:15404. doi: 10.1038/srep15404. Sci Rep. 2015. PMID: 26486271 Free PMC article.
Conserved NPPB+ Border Zone Switches From MEF2- to AP-1-Driven Gene Program.
van Duijvenboden K, de Bakker DEM, Man JCK, Janssen R, Günthel M, Hill MC, Hooijkaas IB, van der Made I, van der Kraak PH, Vink A, Creemers EE, Martin JF, Barnett P, Bakkers J, Christoffels VM. van Duijvenboden K, et al. Among authors: creemers ee. Circulation. 2019 Sep 9;140(10):864-879. doi: 10.1161/CIRCULATIONAHA.118.038944. Epub 2019 Jul 1. Circulation. 2019. PMID: 31259610
Loss-of-function variants in myocardin cause congenital megabladder in humans and mice.
Houweling AC, Beaman GM, Postma AV, Gainous TB, Lichtenbelt KD, Brancati F, Lopes FM, van der Made I, Polstra AM, Robinson ML, Wright KD, Ellingford JM, Jackson AR, Overwater E, Genesio R, Romano S, Camerota L, D'Angelo E, Meijers-Heijboer EJ, Christoffels VM, McHugh KM, Black BL, Newman WG, Woolf AS, Creemers EE. Houweling AC, et al. Among authors: creemers ee. J Clin Invest. 2019 Dec 2;129(12):5374-5380. doi: 10.1172/JCI128545. J Clin Invest. 2019. PMID: 31513549 Free PMC article.
Genetic Dissection of a Super Enhancer Controlling the Nppa-Nppb Cluster in the Heart.
Man JCK, van Duijvenboden K, Krijger PHL, Hooijkaas IB, van der Made I, de Gier-de Vries C, Wakker V, Creemers EE, de Laat W, Boukens BJ, Christoffels VM. Man JCK, et al. Among authors: creemers ee. Circ Res. 2021 Jan 8;128(1):115-129. doi: 10.1161/CIRCRESAHA.120.317045. Epub 2020 Oct 27. Circ Res. 2021. PMID: 33107387
80 results