Gunosewoyo H - Search Results

1

Therapeutic potential of coumestan Pks13 inhibitors for tuberculosis.

Lun S, Xiao S, Zhang W, Wang S, Gunosewoyo H, Yu LF, Bishai WR. Lun S, et al. Among authors: gunosewoyo h. Antimicrob Agents Chemother. 2023 May 1;95(5):e02190-20. doi: 10.1128/AAC.02190-20. Epub 2021 Feb 8. Antimicrob Agents Chemother. 2023. PMID: 33558290 Free PMC article.

2

Preliminary structure-activity relationships and biological evaluation of novel antitubercular indolecarboxamide derivatives against drug-susceptible and drug-resistant Mycobacterium tuberculosis strains.

Onajole OK, Pieroni M, Tipparaju SK, Lun S, Stec J, Chen G, Gunosewoyo H, Guo H, Ammerman NC, Bishai WR, Kozikowski AP. Onajole OK, et al. Among authors: gunosewoyo h. J Med Chem. 2013 May 23;56(10):4093-103. doi: 10.1021/jm4003878. Epub 2013 May 3. J Med Chem. 2013. PMID: 23611124

3

From α4β2 Nicotinic Ligands to the Discovery of σ1 Receptor Ligands: Pharmacophore Analysis and Rational Design.

Yu LF, Zhang HK, Gunosewoyo H, Kozikowski AP. Yu LF, et al. Among authors: gunosewoyo h. ACS Med Chem Lett. 2012 Dec 13;3(12):1054-1058. doi: 10.1021/ml3002715. ACS Med Chem Lett. 2012. PMID: 23641311 Free PMC article.

4

Indoleamides are active against drug-resistant Mycobacterium tuberculosis.

Lun S, Guo H, Onajole OK, Pieroni M, Gunosewoyo H, Chen G, Tipparaju SK, Ammerman NC, Kozikowski AP, Bishai WR. Lun S, et al. Among authors: gunosewoyo h. Nat Commun. 2013;4:2907. doi: 10.1038/ncomms3907. Nat Commun. 2013. PMID: 24352433 Free PMC article.

5

Development of Novel Alkoxyisoxazoles as Sigma-1 Receptor Antagonists with Antinociceptive Efficacy.

Sun H, Shi M, Zhang W, Zheng YM, Xu YZ, Shi JJ, Liu T, Gunosewoyo H, Pang T, Gao ZB, Yang F, Tang J, Yu LF. Sun H, et al. Among authors: gunosewoyo h. J Med Chem. 2016 Jul 14;59(13):6329-43. doi: 10.1021/acs.jmedchem.6b00571. Epub 2016 Jun 30. J Med Chem. 2016. PMID: 27309376

6

Synthesis and biological evaluation of novel hybrids of highly potent and selective α4β2-Nicotinic acetylcholine receptor (nAChR) partial agonists.

Zhang HK, Eaton JB, Fedolak A, Gunosewoyo H, Onajole OK, Brunner D, Lukas RJ, Yu LF, Kozikowski AP. Zhang HK, et al. Among authors: gunosewoyo h. Eur J Med Chem. 2016 Nov 29;124:689-697. doi: 10.1016/j.ejmech.2016.09.016. Epub 2016 Sep 9. Eur J Med Chem. 2016. PMID: 27639361 Free PMC article.

7

Kinase targets in CNS drug discovery.

Gunosewoyo H, Yu L, Munoz L, Kassiou M. Gunosewoyo H, et al. Future Med Chem. 2017 Mar;9(3):303-314. doi: 10.4155/fmc-2016-0214. Epub 2017 Feb 8. Future Med Chem. 2017. PMID: 28176536

8

Amidoalkylindoles as Potent and Selective Cannabinoid Type 2 Receptor Agonists with in Vivo Efficacy in a Mouse Model of Multiple Sclerosis.

Shi Y, Duan YH, Ji YY, Wang ZL, Wu YR, Gunosewoyo H, Xie XY, Chen JZ, Yang F, Li J, Tang J, Xie X, Yu LF. Shi Y, et al. Among authors: gunosewoyo h. J Med Chem. 2017 Aug 24;60(16):7067-7083. doi: 10.1021/acs.jmedchem.7b00724. Epub 2017 Aug 3. J Med Chem. 2017. PMID: 28726401

9

Tying up tranylcypromine: Novel selective histone lysine specific demethylase 1 (LSD1) inhibitors.

Ji YY, Lin SD, Wang YJ, Su MB, Zhang W, Gunosewoyo H, Yang F, Li J, Tang J, Zhou YB, Yu LF. Ji YY, et al. Among authors: gunosewoyo h. Eur J Med Chem. 2017 Dec 1;141:101-112. doi: 10.1016/j.ejmech.2017.09.073. Epub 2017 Oct 3. Eur J Med Chem. 2017. PMID: 29031059

10

Identification of Novel Coumestan Derivatives as Polyketide Synthase 13 Inhibitors against Mycobacterium tuberculosis.

Zhang W, Lun S, Wang SH, Jiang XW, Yang F, Tang J, Manson AL, Earl AM, Gunosewoyo H, Bishai WR, Yu LF. Zhang W, et al. Among authors: gunosewoyo h. J Med Chem. 2018 Feb 8;61(3):791-803. doi: 10.1021/acs.jmedchem.7b01319. Epub 2018 Jan 29. J Med Chem. 2018. PMID: 29328655

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