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Glioblastoma hijacks microglial gene expression to support tumor growth.
Maas SLN, Abels ER, Van De Haar LL, Zhang X, Morsett L, Sil S, Guedes J, Sen P, Prabhakar S, Hickman SE, Lai CP, Ting DT, Breakefield XO, Broekman MLD, El Khoury J. Maas SLN, et al. Among authors: abels er. J Neuroinflammation. 2020 Apr 16;17(1):120. doi: 10.1186/s12974-020-01797-2. J Neuroinflammation. 2020. PMID: 32299465 Free PMC article.
Glioma EVs Contribute to Immune Privilege in the Brain.
Abels ER, Broekman MLD, Breakefield XO, Maas SLN. Abels ER, et al. Trends Cancer. 2019 Jul;5(7):393-396. doi: 10.1016/j.trecan.2019.05.006. Epub 2019 Jun 4. Trends Cancer. 2019. PMID: 31311653 Free PMC article. Review.
CRISPR-Cas knockout of miR21 reduces glioma growth.
Nieland L, van Solinge TS, Cheah PS, Morsett LM, El Khoury J, Rissman JI, Kleinstiver BP, Broekman MLD, Breakefield XO, Abels ER. Nieland L, et al. Among authors: abels er. Mol Ther Oncolytics. 2022 Apr 6;25:121-136. doi: 10.1016/j.omto.2022.04.001. eCollection 2022 Jun 16. Mol Ther Oncolytics. 2022. PMID: 35572197 Free PMC article.
Glioblastomas exploit truncated O-linked glycans for local and distant immune modulation via the macrophage galactose-type lectin.
Dusoswa SA, Verhoeff J, Abels E, Méndez-Huergo SP, Croci DO, Kuijper LH, de Miguel E, Wouters VMCJ, Best MG, Rodriguez E, Cornelissen LAM, van Vliet SJ, Wesseling P, Breakefield XO, Noske DP, Würdinger T, Broekman MLD, Rabinovich GA, van Kooyk Y, Garcia-Vallejo JJ. Dusoswa SA, et al. Proc Natl Acad Sci U S A. 2020 Feb 18;117(7):3693-3703. doi: 10.1073/pnas.1907921117. Epub 2020 Feb 4. Proc Natl Acad Sci U S A. 2020. PMID: 32019882 Free PMC article.
Directly visualized glioblastoma-derived extracellular vesicles transfer RNA to microglia/macrophages in the brain.
van der Vos KE, Abels ER, Zhang X, Lai C, Carrizosa E, Oakley D, Prabhakar S, Mardini O, Crommentuijn MH, Skog J, Krichevsky AM, Stemmer-Rachamimov A, Mempel TR, El Khoury J, Hickman SE, Breakefield XO. van der Vos KE, et al. Among authors: abels er. Neuro Oncol. 2016 Jan;18(1):58-69. doi: 10.1093/neuonc/nov244. Epub 2015 Oct 3. Neuro Oncol. 2016. PMID: 26433199 Free PMC article.
Multidimensional communication in the microenvirons of glioblastoma.
Broekman ML, Maas SLN, Abels ER, Mempel TR, Krichevsky AM, Breakefield XO. Broekman ML, et al. Among authors: abels er. Nat Rev Neurol. 2018 Aug;14(8):482-495. doi: 10.1038/s41582-018-0025-8. Nat Rev Neurol. 2018. PMID: 29985475 Free PMC article. Review.
15 results